[HTML][HTML] The diversified role of mitochondria in ferroptosis in cancer

Y Liu, S Lu, L Wu, L Yang, L Yang, J Wang - Cell death & disease, 2023 - nature.com
Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation,
and it has been studied extensively since its discovery in 2012. Induced by iron overload …

[HTML][HTML] An overview of artificial intelligence in diabetic retinopathy and other ocular diseases

B Sheng, X Chen, T Li, T Ma, Y Yang, L Bi… - Frontiers in Public …, 2022 - frontiersin.org
Artificial intelligence (AI), also known as machine intelligence, is a branch of science that
empowers machines using human intelligence. AI refers to the technology of rendering …

Oxidative stress and regeneration

M Jaganjac, L Milkovic, N Zarkovic… - Free Radical Biology and …, 2022 - Elsevier
Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

[HTML][HTML] Ferroptosis: a double-edged sword mediating immune tolerance of cancer

Q Dang, Z Sun, Y Wang, L Wang, Z Liu, X Han - Cell death & disease, 2022 - nature.com
The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …

Polydopamine nanoparticles targeting ferroptosis mitigate intervertebral disc degeneration via reactive oxygen species depletion, iron ions chelation, and GPX4 …

X Yang, Y Chen, J Guo, J Li, P Zhang… - Advanced …, 2023 - Wiley Online Library
Intervertebral disc degeneration (IVDD)‐induced lower back pain (LBP) is a common
problem worldwide. The underlying mechanism is partially accredited to ferroptosis, based …

[HTML][HTML] Role of oxidative damage in alzheimer's disease and neurodegeneration: From pathogenic mechanisms to biomarker discovery

FR Buccellato, M D'Anca, C Fenoglio, E Scarpini… - Antioxidants, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

[HTML][HTML] Targeting ferroptosis as a vulnerability in pulmonary diseases

L Yang, L Cao, X Zhang, B Chu - Cell Death & Disease, 2022 - nature.com
Ferroptosis is an iron-dependent regulated cell death marked by excessive oxidative
phospholipids (PLs). The polyunsaturated fatty acids-containing phospholipids (PUFA-PLs) …

Targeting molecular mediators of ferroptosis and oxidative stress for neurological disorders

J Li, B Jia, Y Cheng, Y Song, Q Li… - Oxidative Medicine and …, 2022 - Wiley Online Library
With the acceleration of population aging, nervous system diseases including Alzheimer's
disease (AD), Parkinson's disease (PD), Huntington's disease (HD), anxiety, depression …

[HTML][HTML] ACTL6A protects gastric cancer cells against ferroptosis through induction of glutathione synthesis

Z Yang, S Zou, Y Zhang, J Zhang, P Zhang… - Nature …, 2023 - nature.com
Gastric cancer (GC), one of the most common malignant tumors in the world, exhibits a rapid
metastasis rate and causes high mortality. Diagnostic markers and potential therapeutic …

Pharmacological inhibition of ferroptosis as a therapeutic target for neurodegenerative diseases and strokes

Y Wang, S Wu, Q Li, H Sun, H Wang - Advanced Science, 2023 - Wiley Online Library
Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …