The lipocalin apolipoprotein D functional portrait: a systematic review
D Sanchez, MD Ganfornina - Frontiers in Physiology, 2021 - frontiersin.org
Apolipoprotein D is a chordate gene early originated in the Lipocalin protein family. Among
other features, regulation of its expression in a wide variety of disease conditions in humans …
other features, regulation of its expression in a wide variety of disease conditions in humans …
Recent developments of neuroprotective agents for degenerative retinal disorders
K Ou, Y Li, L Liu, H Li, K Cox, J Wu, J Liu… - Neural Regeneration …, 2022 - journals.lww.com
Retinal degeneration is a debilitating ocular complication characterized by the progressive
loss of photoreceptors and other retinal neurons, which are caused by a group of retinal …
loss of photoreceptors and other retinal neurons, which are caused by a group of retinal …
[HTML][HTML] The association of physical activity with glaucoma and related traits in the UK Biobank
Purpose To examine the association of physical activity (PA) with glaucoma and related
traits, to assess whether genetic predisposition to glaucoma modified these associations …
traits, to assess whether genetic predisposition to glaucoma modified these associations …
Cytokine and Complement Response in the Glaucomatous βB1-CTGF Mouse Model
S Reinehr, JD Doerner, AM Mueller-Buehl… - Frontiers in Cellular …, 2021 - frontiersin.org
Glaucoma is a complex neurodegenerative disease leading to a loss of retinal ganglion
cells (RGCs) and optic nerve axons. An activation of the complement system seems to …
cells (RGCs) and optic nerve axons. An activation of the complement system seems to …
The role of complement dysregulation in glaucoma
C Hoppe, M Gregory-Ksander - International Journal of Molecular …, 2024 - mdpi.com
Glaucoma is a progressive neurodegenerative disease characterized by damage to the
optic nerve that results in irreversible vision loss. While the exact pathology of glaucoma is …
optic nerve that results in irreversible vision loss. While the exact pathology of glaucoma is …
Antibody and protein profiles in glaucoma: screening of biomarkers and identification of signaling pathways
N Auler, H Tonner, N Pfeiffer, FH Grus - Biology, 2021 - mdpi.com
Simple Summary Glaucoma is a chronic eye disease that is one of the leading causes of
blindness worldwide. Currently, the only therapeutic option is to lower intraocular pressure …
blindness worldwide. Currently, the only therapeutic option is to lower intraocular pressure …
Proteome alterations in the aqueous humor reflect structural and functional phenotypes in patients with advanced normal-tension glaucoma
SH Lee, JH Jung, TK Park, CE Moon, K Han, J Lee… - Scientific reports, 2022 - nature.com
Previous reports have shown possible association between altered protein levels in
aqueous humor (AH) and normal-tension glaucoma (NTG), but the underlying pathogenetic …
aqueous humor (AH) and normal-tension glaucoma (NTG), but the underlying pathogenetic …
Preservation of optic nerve structure by complement inhibition in experimental glaucoma
CJ Gassel, S Reinehr, SC Gomes, HB Dick… - Cell and tissue …, 2020 - Springer
Glaucoma is characterized by a progressive damage of the retina and the optic nerve.
Despite a huge research interest, the exact pathomechanisms are still unknown. In the …
Despite a huge research interest, the exact pathomechanisms are still unknown. In the …
Proteome characterization of glaucoma aqueous humor
X Liu, X Liu, Y Wang, H Sun, Z Guo, X Tang, J Li… - Molecular & Cellular …, 2021 - ASBMB
Glaucoma is the leading cause of irreversible blindness worldwide. The proteome
characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 …
characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 …
Advances in aqueous humor proteomics for biomarker discovery and disease mechanisms exploration: a spotlight on primary open angle glaucoma
VM Beutgen, J Graumann - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Altered protein levels in the aqueous humor (AH) may be a valuable source of novel
biomarkers in neurodegenerative retinal disease. The proximity of this body fluid to the …
biomarkers in neurodegenerative retinal disease. The proximity of this body fluid to the …