Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

Cells constantly adapt their metabolism to meet their energy needs and respond to nutrient
availability. Eukaryotes have evolved a very sophisticated system to sense low cellular ATP …

Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant
phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co …

Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …

Obesity, a worldwide health concern with a constantly rising prevalence, is a multifactorial
chronic disease associated with a wide range of physiological disruptions, including energy …

Chemotherapy is the first-tier treatment regime for gastric cancer (GC) patients at advance
stages. Mesenchymal stem cell (MSC) cam affect drug-resistance of GC cells in tumor …

Fatty acids (FAs) provide cellular energy under starvation, yet how they mobilize and move
into mitochondria in starved cells, driving oxidative respiration, is unclear. Here, we clarify …

Cellular metabolism is increasingly recognized as a controller of immune cell fate and
function. MicroRNA-33 (miR-33) regulates cellular lipid metabolism and represses genes …

Brown (BAT) and white (WAT) adipose tissues play distinct roles in maintaining whole-body
energy homeostasis, and their dysfunction can contribute to non-alcoholic fatty liver disease …

Obesity occurs when excess energy accumulates in white adipose tissue (WAT), whereas
brown adipose tissue (BAT), which is specialized in dissipating energy through …