ABSTRACT Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary
glomerulonephritis worldwide and it is characterized by mesangial IgA deposition …

Microorganisms found in the human gastrointestinal tract (GIT) are symbiotic under steady
state conditions and have role in the homeostasis of the human host. The term microbiome …

Chronic kidney disease (CKD) is a worldwide public health issue and has ultimately
progressed to an end-stage renal disease that requires life-long dialysis or renal …

Background: Although recent research suggests that alterations in gut microbiota and
metabolites play a critical role in the pathophysiology of immunoglobulin A nephropathy …

Abstract Background The Fufang-zhenzhu-tiaozhi formula (FTZ), a traditional Chinese
medicine (TCM) commonly used to treat metabolic diseases, potentially impacts the …

A PRoliferation-Inducing Ligand (APRIL), the thirteenth member of the tumor necrosis factor
superfamily, plays a key role in the regulation of activated B cells, the survival of long-lived …

Background This study aimed to investigate a causal relationship between IBD and multiple
kidney diseases using two-sample Mendelian randomization (MR) analyses. Methods We …

The article summarizes the current evidence on the impact of microbiota alterations on
immune-mediated primary glomerulonephritis in children. In particular, the focus is on the …

Immunoglobulin A nephropathy (IgAN) is the commonest primary glomerular disease
worldwide and responsible for a significant proportion of the global end-stage kidney …

Systemic erythematosus lupus (SLE) is an autoimmune disease involving multiple organs
that poses a serious risk to the health and life of patients. A growing number of studies have …