Targeting fibrosis: The bridge that connects pancreatitis and pancreatic cancer

C Huang, J Iovanna, P Santofimia-Castaño - International Journal of …, 2021 - mdpi.com
Pancreatic fibrosis is caused by the excessive deposits of extracellular matrix (ECM) and
collagen fibers during repeated necrosis to repair damaged pancreatic tissue. Pancreatic …

Annual report to the nation on the status of cancer, part 1: National cancer statistics

KA Cronin, S Scott, AU Firth, H Sung, SJ Henley… - Cancer, 2022 - Wiley Online Library
Abstract Background The American Cancer Society, the Centers for Disease Control and
Prevention, the National Cancer Institute, and the North American Association of Central …

Venous resection for pancreatic cancer, a safe and feasible option? A systematic review and meta-analysis

ES Zwart, BS Yilmaz, A Halimi, R Ahola, B Kurlinkus… - Pancreatology, 2022 - Elsevier
Background In pancreatic ductal adenocarcinoma patients with suspected venous
infiltration, a R0 resection is most of the time not possible without venous resection (VR). To …

Clinical benefits of pulmonary resection for lung metastases from pancreatic cancer

T Konishi, S Takano, T Takayashiki, S Kuboki… - … Archives of Surgery, 2023 - Springer
Purpose Systemic chemotherapy is generally used for metastatic pancreatic cancer;
however, pulmonary resection may be a treatment option for lung oligometastases from …

A scan of all coding region variants of the human genome, identifies 13q12. 2-rs9579139 and 15q24. 1-rs2277598 as novel risk loci for pancreatic ductal …

M Giaccherini, L Gori, M Gentiluomo… - …, 2023 - academic.oup.com
Coding sequence variants comprise a small fraction of the germline genetic variability of the
human genome. However, they often cause deleterious change in protein function and are …

A simple risk score for detecting radiological occult metastasis in patients with resectable or borderline resectable pancreatic ductal adenocarcinoma

T Sakaguchi, S Satoi, D Hashimoto… - Journal of Hepato …, 2022 - Wiley Online Library
Background We advocated carbohydrate antigen (CA) 19‐9≥ 150 U/mL and tumor size≥
30 mm as “high‐risk markers” for predicting unresectability among patients with …

The postoperative platelet-to-lymphocyte ratio predicts the outcome of patients undergoing pancreaticoduodenectomy for pancreatic head cancer

Y Shirai, R Hamura, Y Tanji, T Taniai, M Yanagaki… - Surgery Today, 2024 - Springer
Purpose The preoperative platelet-to-lymphocyte ratio (PLR) has been reported as an
important prognostic index for pancreatic ductal adenocarcinoma (PDAC); however, the …

Preoperative prediction of long-term survival after surgery in patients with resectable pancreatic ductal adenocarcinoma

T Konishi, S Takano, T Takayashiki, D Suzuki… - Annals of Surgical …, 2024 - Springer
Background Although some clinical trials have demonstrated the benefits of neoadjuvant
therapy for resectable pancreatic ductal adenocarcinoma (PDAC), its optimal candidate has …

Prognostic significance of occult vertebral fracture in patients undergoing pancreatic resection for pancreatic cancer

S Ishizaki, K Furukawa, K Haruki, M Tsunematsu… - Pancreatology, 2024 - Elsevier
Objective The prognostic impact of occult vertebral fracture (OVF) in patients with
malignancies is a new cutting edge in cancer research. This study was performed to analyze …

Survival impact of occult liver metastasis and peritoneal dissemination compared with radiologically defined distant organ metastasis in pancreatic ductal …

D Hashimoto, T Sakaguchi, S Satoi, T Yamamoto… - Pancreatology, 2023 - Elsevier
Background Characteristics and prognoses of patients with occult metastases (OM) of
pancreatic ductal adenocarcinoma (PDAC) compared with radiologically defined …