Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

Crimean–Congo haemorrhagic fever virus

DW Hawman, H Feldmann - Nature Reviews Microbiology, 2023 - nature.com
Crimean–Congo haemorrhagic fever (CCHF) is a severe tick-borne illness with a wide
geographical distribution and case fatality rates of 30% or higher. Caused by infection with …

[HTML][HTML] The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review

H Liao, J Ye, L Gao, Y Liu - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Scutellaria baicalensis Georgi., a plant used in traditional Chinese medicine, has multiple
biological activities, including anti-inflammatory, antiviral, antitumor, antioxidant, and …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
The cytokine storm has captured the attention of the public and the scientific community
alike, and while the general notion of an excessive or uncontrolled release of …

[HTML][HTML] The pro-and anti-inflammatory properties of the cytokine interleukin-6

J Scheller, A Chalaris, D Schmidt-Arras… - Biochimica et Biophysica …, 2011 - Elsevier
Interleukin-6 is a cytokine not only involved in inflammation and infection responses but also
in the regulation of metabolic, regenerative, and neural processes. In classic signaling …

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

S Kaptoge, SRK Seshasai, P Gao… - European heart …, 2014 - academic.oup.com
Aims Because low-grade inflammation may play a role in the pathogenesis of coronary heart
disease (CHD), and pro-inflammatory cytokines govern inflammatory cascades, this study …

Emerging cytokine networks in colorectal cancer

NR West, S McCuaig, F Franchini… - Nature Reviews …, 2015 - nature.com
Cytokine networks are crucial aspects of tumour immunology, particularly for colorectal
cancer (CRC), in which inflammation and antitumour immunity are key determinants of …

IL-6/IL-6 receptor system and its role in physiological and pathological conditions

M Mihara, M Hashizume, H Yoshida, M Suzuki… - Clinical …, 2012 - portlandpress.com
IL (interleukin)-6, which was originally identified as a B-cell differentiation factor, is a
multifunctional cytokine that regulates the immune response, haemopoiesis, the acute …

Long non-coding RNAs in the regulation of the immune response

JA Heward, MA Lindsay - Trends in immunology, 2014 - cell.com
It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biological
responses, and that they do so by a diverse range of mechanisms. In the field of …

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

SA Jones, J Scheller… - The Journal of clinical …, 2011 - Am Soc Clin Investig
The successful treatment of certain autoimmune conditions with the humanized anti–IL-6
receptor (IL-6R) antibody tocilizumab has emphasized the clinical importance of cytokines …