Oral delivery of infliximab using nano-in-microparticles for the treatment of inflammatory bowel disease

X Li, M Yu, Z Zhu, C Lu, M Jin, Y Rao, Q Zhao, X Lu… - Carbohydrate …, 2021 - Elsevier
The anti-tumor necrosis factor-α (anti-TNF-α) blocker, has shown great efficacy for the
treatment of inflammatory bowel disease (IBD). However, systemic exposure to it can cause …

The nuclear cytokine IL-37a controls lethal cytokine storms primarily via IL-1R8-independent transcriptional upregulation of PPARγ

R Wei, X Han, M Li, Y Ji, L Zhang… - Cellular & Molecular …, 2023 - nature.com
Cytokine storms are crucial in the development of various inflammatory diseases, including
sepsis and autoimmune disorders. The immunosuppressive cytokine INTERLEUKIN (IL)-37 …

[HTML][HTML] Infection of Human Neutrophils With Leishmania infantum or Leishmania major Strains Triggers Activation and Differential Cytokines Release

R Oualha, M Barhoumi, S Marzouki… - Frontiers in cellular …, 2019 - frontiersin.org
Leishmaniases are neglected diseases, caused by intracellular protozoan parasites of the
Leishmania (L.) genus. Although the principal host cells of the parasites are macrophages …

Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo

TB Sundberg, Y Liang, H Wu, HG Choi… - ACS chemical …, 2016 - ACS Publications
Salt-inducible kinases (SIKs) are promising therapeutic targets for modulating cytokine
responses during innate immune activation. The study of SIK inhibition in animal models of …

[HTML][HTML] Follicular dendritic cells in health and disease

MEM El Shikh, C Pitzalis - Frontiers in immunology, 2012 - frontiersin.org
Follicular dendritic cells (FDCs) are unique immune cells that contribute to the regulation of
humoral immune responses. These cells are located in the B-cell follicles of secondary …

[HTML][HTML] Effects of endocrine disruptor compounds, alone or in combination, on human macrophage-like THP-1 cell response

N Couleau, J Falla, A Beillerot, E Battaglia… - PLoS …, 2015 - journals.plos.org
The aim of the present study was to evaluate the immunological effects on human
macrophages of four endocrine disruptor compounds (EDCs) using the differentiated human …

Inflammation and cardiac outcome

PJ Hohensinner, A Niessner, K Huber… - Current opinion in …, 2011 - journals.lww.com
Inflammation and cardiac outcome : Current Opinion in Infectious Diseases Inflammation
and cardiac outcome : Current Opinion in Infectious Diseases Log in or Register Subscribe …

Objectively measured muscle fatigue in Crohn's disease: correlation with self-reported fatigue and associated factors for clinical application

DR Van Langenberg, P Della Gatta… - Journal of Crohn's …, 2014 - academic.oup.com
Background & aims The association of fatigue with decreased physical performance and
underlying mechanisms are poorly understood in Crohn's disease (CD). We aimed to …

Targeting the GM-CSF receptor for the treatment of CNS autoimmunity

I Ifergan, TS Davidson, H Kebir, D Xu… - Journal of …, 2017 - Elsevier
In multiple sclerosis (MS), there is a growing interest in inhibiting the pro-inflammatory
effects of granulocyte-macrophage colony-stimulating factor (GM-CSF). We sought to …

[HTML][HTML] Therapeutic effects and molecular mechanism of chlorogenic acid on polycystic ovarian syndrome: role of HIF-1alpha

Z Zhang, C Shi, Z Wang - Nutrients, 2023 - mdpi.com
Chlorogenic acid (CGA) is a powerful antioxidant polyphenol molecule found in many diets
and liquid beverages, playing a preventive and therapeutic role in various diseases caused …