The role of glucocorticoids in inflammatory diseases

SD Reichardt, A Amouret, C Muzzi, S Vettorazzi… - Cells, 2021 - mdpi.com
For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a …

Glucocorticoids and COVID-19

S Bruscoli, PG Puzzovio, M Zaimi, K Tiligada… - Pharmacological …, 2022 - Elsevier
Abstract Coronavirus Disease 19 (COVID-19) is associated with high morbidity and mortality
rates globally, representing the greatest health and economic challenge today. Several …

Discriminative accuracy of the CAPTURE tool for identifying chronic obstructive pulmonary disease in US primary care settings

FJ Martinez, MLK Han, C Lopez, S Murray, D Mannino… - Jama, 2023 - jamanetwork.com
Importance Chronic obstructive pulmonary disease (COPD) is underdiagnosed in primary
care. Objective To evaluate the operating characteristics of the CAPTURE (COPD …

Update on asthma–COPD overlap (ACO): a narrative review

E Mekov, A Nuñez, DD Sin, M Ichinose… - … Journal of Chronic …, 2021 - Taylor & Francis
Although chronic obstructive pulmonary disease (COPD) and asthma are well-characterized
diseases, they can coexist in a given patient. The term asthma–COPD overlap (ACO) was …

Epidemiology, healthcare resource utilization, and mortality of asthma and COPD in COVID-19: a systematic literature review and meta-analyses

DMG Halpin, AP Rabe, WJ Loke, S Grieve… - Journal of asthma …, 2022 - Taylor & Francis
Purpose There has been concern that asthma and chronic obstructive pulmonary disease
[COPD] increase the risk of developing and exacerbating COVID-19. The effect of …

Emerging applications and prospects of NFκB decoy oligodeoxynucleotides in managing respiratory diseases

JK Datsyuk, KR Paudel, R Rajput, S Kokkinis… - Chemico-biological …, 2023 - Elsevier
Chronic respiratory diseases like asthma and Chronic Obstructive Pulmonary Disease
(COPD) have been a burden to society for an extended period. Currently, there are only …

Reversible airflow obstruction predicts future chronic obstructive pulmonary disease development in the SPIROMICS cohort: an observational cohort study

RG Buhr, IZ Barjaktarevic, PM Quibrera… - American journal of …, 2022 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is defined by fixed spirometric
ratio, FEV1/FVC< 0.70 after inhaled bronchodilators. However, the implications of variable …

The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS)

TE Albertson, JA Chenoweth, SJ Pearson… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) is a
disease phenotype that shares T helper lymphocyte cell Th1/neutrophilic/non-Type-2 …

Effects of a Peptide Derived from the Primary Sequence of a Kallikrein Inhibitor Isolated from Bauhinia bauhinioides (pep-BbKI) in an Asthma–COPD Overlap (ACO) …

LLS Silva, JAS Barbosa, JMLG João… - International Journal of …, 2023 - mdpi.com
(1) There are several patients with asthma–COPD overlap (ACO). A peptide derived from the
primary sequence of a kallikrein inhibitor isolated from Bauhinia bauhinioides (pep-BbKI) …

Phosphodiesterase-4 inhibitors for non-COPD respiratory diseases

T Kawamatawong - Frontiers in pharmacology, 2021 - frontiersin.org
Selective phosphodiesterase (PDE) inhibitors are a class of nonsteroid anti-inflammatory
drugs for treating chronic inflammatory diseases. Modulation of systemic and airway …