Problematic severe asthma in children, not one problem but many: a GA2LEN initiative

G Hedlin, A Bush, KL Carlsen… - European …, 2010 - Eur Respiratory Soc
Although most children with asthma are easy to treat with low doses of safe medications,
many remain symptomatic despite every therapeutic effort. The nomenclature regarding this …

ICON: chronic rhinosinusitis

C Bachert, R Pawankar, L Zhang, C Bunnag… - World Allergy …, 2014 - Springer
Chronic rhinosinusitis (CRS) is a public health problem that has a significant socio-
economic impact. Moreover, the complexity of this disease due to its heterogeneous nature …

The role of upper airway pathology as a co-morbidity in severe asthma

A Licari, I Brambilla, M De Filippo… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Severe asthma is a complex heterogeneous disease that is refractory to
standard treatment and is complicated by multiple co-morbidities and risk factors. Several co …

[HTML][HTML] Pediatric rhinosinusitis and asthma

D Poddighe, I Brambilla, A Licari, GL Marseglia - Respiratory Medicine, 2018 - Elsevier
Both asthma and rhinosinusitis are complex and heterogeneous diseases and, importantly,
they often coexist: these diseases can be concomitant in 35–65% of affected children …

Current opinions for the management of asthma associated with ear, nose and throat comorbidities

A Tiotiu, D Plavec, S Novakova… - European …, 2018 - Eur Respiratory Soc
Ear, nose and throat (ENT) comorbidities are common in patients with asthma and are
frequently associated with poorer asthma outcomes. All these comorbidities are “treatable …

An update on the role of chronic rhinosinusitis with nasal polyps as a co-morbidity in severe asthma

R Castagnoli, A Licari, I Brambilla, M Tosca… - Expert Review of …, 2020 - Taylor & Francis
Introduction Chronic rhinosinusitis and asthma are heterogeneous diseases with complex
pathogenesis. The presence of chronic rhinosinusitis with nasal polyps has been associated …

[HTML][HTML] 慢性鼻窦炎患者生存质量研究进展

王梦瑶, 王斌全, 王磊, 闫媛媛, 王倩… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
With the development of modern medical technology, people not only require the extention
of life, but also pay more attention to the quality of life. Chronic rhino-sinusitis is a common …

The frequency of chronic rhinosinusitis/nasal polyp in COPD and its effect on the severity of COPD

A Kelemence, O Abadoglu, C Gumus… - COPD: Journal of …, 2011 - Taylor & Francis
This study aimed to investigate the effect of chronic rhinosinusitis/nasal polyposis on the
severity of COPD and to find out whether the 'united airway disease'hypothesis is valid for …

Nasal epithelial cells can act as a physiological surrogate for paediatric asthma studies

S Thavagnanam, JC Parker, ME McBrien, G Skibinski… - PLoS …, 2014 - journals.plos.org
Introduction Differentiated paediatric epithelial cells can be used to study the role of
epithelial cells in asthma. Nasal epithelial cells are easier to obtain and may act as a …

Nasal polyps

MS Georgy, AT Peters - Allergy and asthma proceedings, 2012 - search.proquest.com
Nasal polyps are inflammatory outgrowths of paranasal sinus mucosa caused by chronic
mucosal inflammation that typically arise from the middle meatus and ethmoid region. The …