Real‑world treatment outcomes among patients with metastatic pancreatic cancer in Japan: The Tokushukai real‑world data project

R Shimoyama, Y Imamura, K Uryu… - Molecular and …, 2023 - spandidos-publications.com
The present study aimed to investigate temporal trends in treatment patterns and prognostic
factors for overall survival (OS) among patients with metastatic pancreatic cancer. From the …

[HTML][HTML] A prospective phase II study of biweekly S-1, leucovorin, and gemcitabine in elderly patients with locally advanced or metastatic pancreatic adenocarcinoma …

LY Bai, CP Li, YS Shan, SC Chuang, JS Chen… - European Journal of …, 2022 - Elsevier
Background Elderly patients with advanced pancreatic adenocarcinoma (APC) are
conceived to be frailer and susceptible to treatment toxicity that has led to disparity in lower …

Role of conversion surgery for unresectable pancreatic cancer after long-term chemotherapy

N Tsuchiya, R Matsuyama, T Murakami… - World Journal of …, 2020 - Springer
Background Unresectable pancreatic cancer (UR-PC) has a poor prognosis. Although
conversion surgery has been considered a promising strategy for improving prognosis in UR …

Single-center risk factor analysis for FOLFIRINOX associated febrile neutropenia in patients with pancreatic cancer

J Keum, HS Lee, H Kang, JH Jo, MJ Chung… - Cancer Chemotherapy …, 2020 - Springer
Purpose FOLFIRINOX is the standard therapy in patients with unresectable pancreatic
cancer (PC). However, FOLFIRINOX frequently induces febrile neutropenia (FN) and …

A phase I trial of oxaliplatin, irinotecan, and S-1 combination therapy (OX-IRIS) as chemotherapy for unresectable pancreatic cancer (HGCSG 1403)

Y Kawamoto, H Nakatsumi, K Harada… - The …, 2021 - academic.oup.com
Abstract Lessons Learned Because S-1 is orally administered, OX-IRIS does not necessitate
the continuous infusion of 5-FU and is more convenient. The recommended dose of OX-IRIS …

Phase II clinical trial of gemcitabine plus oxaliplatin in patients with metastatic pancreatic adenocarcinoma with a family history of pancreatic/breast/ovarian/prostate …

N Okano, C Morizane, S Nomura, H Takahashi… - International Journal of …, 2020 - Springer
Background A family/personal history of breast, ovarian, or pancreatic cancer is a useful
predictive marker for response to platinum-based chemotherapy in treating patients with …

[HTML][HTML] Comparing the cost-effectiveness of FOLFIRINOX, nab-paclitaxel plus gemcitabine, gemcitabine and S-1 for the treatment of metastatic pancreatic cancer

M Kurimoto, M Kimura, E Usami… - Molecular and …, 2017 - spandidos-publications.com
The recommended chemotherapy regimens for pancreatic cancer include the combination
of 5-fluorouracil/leucovorin, oxaliplatin and irinotecan (FOLFIRINOX), nab‑paclitaxel (nab …

Phase I study assessing the feasibility of the triple combination chemotherapy of SOXIRI (S-1/oxaliplatin/irinotecan) in patients with unresectable pancreatic ductal …

H Yanagimoto, S Satoi, M Sho, T Akahori… - Cancer chemotherapy …, 2016 - Springer
Background The objective of this study was to determine the recommended dose (RD) of a
biweekly S-1, oxaliplatin, and irinotecan (SOXIRI) regimen in patients with unresectable …

Prognostic factor in patient with recurrent pancreatic adenocarcinoma

T Sumiyoshi, K Uemura, R Shintakuya, K Okada… - … Archives of Surgery, 2023 - Springer
Purpose To elucidate prognostic factors for post-recurrence survival in patients with
pancreatic ductal adenocarcinoma (PDAC). Methods Patients who underwent curative-intent …

Liver metastases from pancreatic ductal adenocarcinoma: is there a place for surgery in the modern era?

K Imai, GA Margonis, J Wang, CL Wolfgang… - Journal of …, 2020 - mednexus.org
Pancreatic ductal adenocarcinoma (PDAC) represents one of the most aggressive
malignancies, and the majority of patients with PDAC present with metastatic disease …