This review summarizes the current understanding of the role of plasma membrane
transporters in regulating intracellular inorganic phosphate ([Pi] In) in mammals. Pi influx is …

This paper reports the trifunctionalization reactions of tertiary enaminones in the fashion of
selective gem-and vicinal diphosphorylation, leading to the tunable synthesis of α, α-and α …

Simple Summary In spontaneous tumor regression, tumors shrink and disappear without
conventional treatments. This phenomenon challenges the view that cancer is an …

Estrogen receptor-positive (ER+) breast cancer intrinsically confers satisfactory clinical
outcomes in response to endocrine therapy. However, a significant proportion of patients …

Background Colorectal cancer is the third most commonly diagnosed cancer. Natural
compounds, administered together with conventional chemotherapeutic agent (s) and/or …

Background/Aim: Radiotherapy is one of the main treatments for estrogen receptor-positive
(ER+) breast cancer. However, in some ER+ breast cancer cases, radiotherapy is insufficient …

Trehalose is a disaccharide with multiple important biological activities. In many cell types,
Trehalose regulates the physiological behaviors of proliferation, apoptosis and autophagy …

Ligand-binding proteins have good to moderate binding affinity for various small molecules,
usually in the millimolar to micromolar range. Many industrially and clinically relevant …

Epidemiological data link processed meat products to various cancers, especially colorectal
cancer; however, such evidence cannot prove causation. Clear mechanistic evidence of …

The intake of dietary phosphate far exceeds recommended levels; however, the long-term
health consequences remain relatively unknown. Here, the chronic physiological response …