Deciphering Acetaminophen-Induced Hepatotoxicity: The Crucial Role of Transcription Factors like Nuclear Factor Erythroid 2–Related Factor 2 as Genetic …
Acetaminophen (APAP) is the most commonly used over-the-counter medication throughout
the world. At therapeutic doses, APAP has potent analgesic and antipyretic effects. The …
the world. At therapeutic doses, APAP has potent analgesic and antipyretic effects. The …
Fucoidan Supplementation Improves Antioxidant Capacity via Regulating the Keap1/Nrf2 Signaling Pathway and Mitochondrial Function in Low-Weaning Weight …
C Yin, Q Bi, W Chen, C Wang, B Castiglioni, Y Li… - Antioxidants, 2024 - mdpi.com
Fucoidan (FC) is known for its antioxidant properties, but it has unclear effects and
mechanisms on weaned piglets. Two experiments were conducted to determine the optimal …
mechanisms on weaned piglets. Two experiments were conducted to determine the optimal …
[HTML][HTML] Hepatoprotective effects of Elaeagnus latifolia fruit extract against acetaminophen-induced hepatotoxicity in mice: Mechanistic insights
N Munkong, K Ruxsanawet, V Ariyabukalakorn… - Journal of Functional …, 2024 - Elsevier
Elaeagnus latifolia fruit extract (EE) has been reported to contain antioxidant and anti-
inflammatory phytochemicals. The present study aimed to examine the anti-hepatotoxic …
inflammatory phytochemicals. The present study aimed to examine the anti-hepatotoxic …
Puerarin alleviates oxaliplatin-induced neuropathic pain by promoting Nrf2/GPX4-mediated antioxidative response
C Dai, F Zhen, L Yu, S Xin - Plos one, 2024 - journals.plos.org
Oxaliplatin (OXA) as the platinum-based agent induces the cumulative neuropathy including
functional impairment and neuropathic pain. OXA treatment triggered oxidative stress and …
functional impairment and neuropathic pain. OXA treatment triggered oxidative stress and …
[HTML][HTML] Puerarin Alleviates Blood Pressure via Inhibition of ROS/TLR4/NLRP3 Inflammasome Signaling Pathway in the Hypothalamic Paraventricular Nucleus of Salt …
HL Gao, Y Yang, H Tian, SL Xu, BW Li, LY Fu, KL Liu… - Nutrients, 2024 - mdpi.com
Background: Puerarin is an isoflavone compound isolated from the roots of a leguminous
plant, the wild kudzu. Various functional activities of this compound in multiple diseases …
plant, the wild kudzu. Various functional activities of this compound in multiple diseases …
Sirtuin 5‐Mediated Desuccinylation of ALDH2 Alleviates Mitochondrial Oxidative Stress Following Acetaminophen‐Induced Acute Liver Injury
Q Yu, J Zhang, J Li, Y Song, J Pan, C Mei… - Advanced …, 2024 - Wiley Online Library
Acetaminophen (APAP) overdose is a major cause of drug‐induced liver injury. Sirtuins 5
(SIRT5) has been implicated in the development of various liver diseases. However, its …
(SIRT5) has been implicated in the development of various liver diseases. However, its …
[HTML][HTML] Effects of puerarin on growth, liver immunity and antioxidant capacity of yellowfin seabream (Acanthopagrus latus) under oxidized fish oil stress
L Kong, J Ma, S Zhou, Z Huang, X Wang, F Quan… - Aquaculture …, 2024 - Elsevier
Puerarin, an isoflavone, exhibits protective effects against liver damage. This study
investigated the effects of puerarin on the growth, liver immunity, and antioxidant capacity of …
investigated the effects of puerarin on the growth, liver immunity, and antioxidant capacity of …
Puerarin: A Stimulator of NRF-2 Against Oxidative Damage in Diseases
O Alejolowo, G Austin, C Nwonuma… - … and Business for …, 2024 - ieeexplore.ieee.org
Puerarin is a naturally occurring isoflavone lavishly present in the genus Pueraria such as
Pueraria lobata and Pueraria mirifica. It has tremendous antioxidant, anti-inflammatory …
Pueraria lobata and Pueraria mirifica. It has tremendous antioxidant, anti-inflammatory …
AGE-DEPENDENCE OF BIOCHEMICAL MANIFESTATIONS OF HEPATOTOXIC INJURY IN RAT EXPOSED TO XENOBIOTICS OF VARIOUS GENESIS
HP KOPYLCHUK, IM NYKOLAICHUK… - Науковий вісник …, 2024 - journals.chnu.edu.ua
Currently, the problem of liver diseases against the backdrop of the toxic effects of medicinal
and industrial (herbicides) xenobiotics on the body is becoming increasingly relevant. The …
and industrial (herbicides) xenobiotics on the body is becoming increasingly relevant. The …