Importance Covert vascular brain injury (VBI) is highly prevalent in community-dwelling
older persons, but its clinical and therapeutic implications are debated. Objective To better …

Background White matter hyperintensities of presumed vascular origin (WMH) are one of the
imaging features of cerebral small vessel disease. Controversies persist about the effects of …

Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

This paper is a proposal for an update on the characterization of cognitive impairments
associated with sporadic cerebral small vessel disease (SVD). We pose a series of …

Purpose Many daily-life clinical decisions in patients with cerebrovascular disease and
cognitive impairment are complex. Evidence-based information sustaining these decisions …

Background Cerebral microbleeds can confer a high risk of intracerebral hemorrhage,
ischemic stroke, death and dementia, but estimated risks remain imprecise and often …

Introduction Many consequences of cerebrovascular disease are identifiable by magnetic
resonance imaging (MRI), but variation in methods limits multicenter studies and pooling of …

Articles were identified through Pubmed searches using these terms: DTI, diffusion, WM
microstructural damage, WM integrity, structural network, brain connectivity AND each of the …

Background Cerebral small vessel disease (CSVD) is prevalent in the elderly and leads to
an increased risk of cognitive impairment and dementia. The volume of white matter …

The era of precision medicine has arrived and conveys tremendous potential, particularly for
stroke neurology. The diagnosis of stroke, its underlying aetiology, theranostic strategies …