Reconstruction of long-bone segmental defects (LBSDs) has been one of the biggest
challenges in orthopaedics. Biomaterials for the reconstruction are required to be strong …

Introduction Despite an adequate orthopedic treatment with functional bracing, some
patients develop a delayed union in humeral shaft fractures. The objective of the present …

Osteoarthritis (OA) is the most prevalent joint disease causing major disability and medical
expenditures. Synovitis is a central feature of OA and is primarily driven by macrophages …

Autologous cancellous bone graft is currently used as a gold standard method for treatment
of bone nonunion. However, there is a limit to the amount of autologous cancellous bone …

Delayed union or nonunion of bone fracture is becoming less frequent, but still remains a
challenging clinical problem. Autologous cancellous bone grafting that is the gold standard …

Aim: We review relevant anatomy of the iliac crest, and describe an interventional technique
to maximize harvesting of desired progenitor cells with ultrasound to guide safe trochar …

Autologous Percutaneous Bone Marrow Injection in Long Bone Fractures with Delayed and
Nonunion Page 1 Autologous Percutaneous Bone Marrow Injection in Long Bone Fractures with …

Introduction: Tibial fracture union is a lengthy process that begins with the initial trauma and
continues for years following clinical and radiological union until the bone regains its …

Background: To compare the results of percutaneous bone marrow aspirate injection with
autologous bone grafting in the treatment of delayed union of femur and tibia diaphyseal …

Use of mesenchymal stem cells from bone marrow has gained significant popularity. The
iliac crest has been determined to be an effective site for harvesting mesenchymal stem …