Control of innate immune response by biomaterial surface topography, energy, and stiffness

JO Abaricia, N Farzad, TJ Heath, J Simmons… - Acta Biomaterialia, 2021 - Elsevier
As the focus of implantable biomaterials has shifted from bioinert implants to bioactive
designs, recent research has highlighted the complex interactions between cell physiologic …

Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery

W Kim, NK Ly, Y He, Y Li, Z Yuan, Y Yeo - Advanced drug delivery reviews, 2023 - Elsevier
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …

[HTML][HTML] In vivo Protein Corona Formation: Characterizations, Effects on Engineered Nanoparticles' Biobehaviors, and Applications

X Bai, J Wang, Q Mu, G Su - Frontiers in bioengineering and …, 2021 - frontiersin.org
Understanding the basic interactions between engineered nanoparticles (ENPs) and
biological systems is essential for evaluating ENPs' safety and developing better …

[HTML][HTML] Use of superparamagnetic iron oxide nanoparticles (SPIONs) via multiple imaging modalities and modifications to reduce cytotoxicity: an educational review

NR Nelson, JD Port, MK Pandey - Journal of Nanotheranostics, 2020 - mdpi.com
The aim of the present educational review on superparamagnetic iron oxide nanoparticles
(SPIONs) is to inform and guide young scientists and students about the potential use and …

Engineering at the nano-bio interface: harnessing the protein corona towards nanoparticle design and function

RL Pinals, L Chio, F Ledesma, MP Landry - Analyst, 2020 - pubs.rsc.org
Unpredictable and uncontrollable protein adsorption on nanoparticles remains a
considerable challenge to achieving effective application of nanotechnologies within …

[HTML][HTML] Smart and multi-functional magnetic nanoparticles for cancer treatment applications: Clinical challenges and future prospects

E Aram, M Moeni, R Abedizadeh, D Sabour… - Nanomaterials, 2022 - mdpi.com
Iron oxide nanoparticle (IONPs) have become a subject of interest in various biomedical
fields due to their magnetism and biocompatibility. They can be utilized as heat mediators in …

[HTML][HTML] Association between Microorganisms and Microplastics: How Does It Change the Host–Pathogen Interaction and Subsequent Immune Response?

W Yang, Y Li, D Boraschi - International Journal of Molecular Sciences, 2023 - mdpi.com
Plastic pollution is a significant problem worldwide because of the risks it poses to the
equilibrium and health of the environment as well as to human beings. Discarded plastic …

The combination of morphology and surface chemistry defines the immunological identity of nanocarriers in human blood

MP Vincent, NB Karabin, SD Allen… - Advanced …, 2021 - Wiley Online Library
Upon exposure to blood, a corona of proteins adsorbs to nanocarrier surfaces to confer a
biological identity that interfaces with the immune system. While the nanocarrier surface …

[HTML][HTML] Understanding the role and impact of poly (ethylene glycol)(PEG) on nanoparticle formulation: Implications for COVID-19 vaccines

E Padín-González, P Lancaster, M Bottini… - … in bioengineering and …, 2022 - frontiersin.org
Poly (ethylene glycol)(PEG) is a widely used polymer in a variety of consumer products and
in medicine. PEGylation refers to the conjugation of PEG to drugs or nanoparticles to …

[HTML][HTML] The intrinsic biological identities of iron oxide nanoparticles and their coatings: unexplored territory for combinatorial therapies

V Mulens-Arias, JM Rojas, DF Barber - Nanomaterials, 2020 - mdpi.com
Over the last 20 years, iron oxide nanoparticles (IONPs) have been the subject of increasing
investigation due to their potential use as theranostic agents. Their unique physical …