ABSTRACT Introduction: Iron (Fe) and manganese (Mn) are essential nutrients for humans.
They act as cofactors for a variety of enzymes. In the central nervous system (CNS), these …

Our previous variable-light intensity lighting program studies indicate the light intensity
preference behavior of broilers for their daily activity including eating and resting. To …

Depression is a devastating mental disorder that affects millions of people worldwide.
Inflammation has been shown to be a key factor involved in the underlying pathophysiology …

Stress during early life has potential to program and alter the response to stressful events
and metabolism in later life. Repeated short exposure of Atlantic salmon to cold water and …

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a key messenger that mediates
several central and peripheral functions in the human body. Emerging evidence indicates …

Seasonal changes in the environment lead to depression-like behaviors in humans and
animals. The underlying mechanisms, however, are unknown. We observed decreased …

Pomegranate (Punica granatum) fruit is of particular interest because of its high nutritional
value and therapeutic actions. Recently, we showed that an aqueous extract of …

Objectives This study aimed to identify patients with major depressive disorder (MDD) by
developing different machine learning (ML) models based on tryptophan hydroxylase-2 …

Depression is an eminently treatable disorder that responds to psychotherapy or
medications; the efficacy of each has been established in hundreds of controlled trials …

Abstract Tryptophan hydroxylase 2 (TPH2) plays a crucial role in the human brain. Although
the association between the TPH2 gene and depression has been suggested in previous …