Targeted oral delivery of a drug via the intestinal lymphatic system (ILS) has the advantages
of protecting against hepatic first‐pass metabolism of the drug and improving its …

Oral ingestion remains as the most convenient route of administration for the application of
pharmaceuticals since it is non-invasive and does not require trained personnel to …

Biological drugs are attracting tremendous attention in disease treatment. However, their
application is significantly limited by their inherent properties, such as high hydrophilicity …

Drug delivery to the brain has been one of the toughest challenges researchers have faced
to develop effective treatments for brain diseases. Owing to the blood–brain barrier (BBB) …

In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

Nanotherapeutics demonstrate poor accumulation in the tumor microenvironment due to
poor extravasation and penetration into the tumor. Therapeutics such as oligonucleotides …

Mineralized enamel and dentin provide protection to the dental pulp, which is vital tissue rich
with cells, vasculature, and nerves in the inner tooth. Dental caries left untreated threaten …

In the developed world, declining prevalence of some parasitic infections correlates with
increased incidence of allergic and autoimmune disorders. Moreover, experimental human …

Despite great potential, the delivery of genetic materials into cells or tissues of interest
remains challenging owing to their susceptibility to nuclease degradation, lack of …

Macromolecules (proteins/peptides) have the potential for the development of new
therapeutics. Due to their specific mechanism of action, macromolecules can be …