This chapter explores the routes of administration for biological therapy including biologics
and biosimilars, with a focus on less invasive and noninvasive delivery in addition to the …

Biopharmaceuticals play a crucial role in preventing, treating, and diagnosing a diverse
range of diseases across various medical disciplines. The market for biopharmaceuticals …

For the delivery of hydrophilic macromolecules, a novel flexible, hydrophilic delivery system
based on gelatin nanoparticles is developed. Stabilization of gelatin in water is addressed …

Diabetes is a leading cause of chronic illness, and the costs associated with its treatment
exceed $245 billion annually in the United States alone. For those patients afflicted with …

With so many biologics in development and no patient-centric way to deliver them, it was
inevitable that innovative delivery solutions would emerge that enable a new …

or entities specific to the pathology. Genomics has been a critical component of target
identification, and has greatly amplified the impact and potential of targeted therapy …

Biologics-based therapeutics, such as proteins and cells, have gained increasing popularity
over the past few years. Formulation and process strategies have been applied to achieve …

Before pharmaceutical companies can produce a product several validation studies have to
be done, such as cleaning validation. The main objective of cleaning validation is to …

The growth of the biopharmaceuticals market and the interest of controlled-release (CR)
formulations combined with the production of microparticles based on biodegradable …

Macromolecular drugs are relatively large and complex molecules compared with
conventional synthetic drugs. An orally administered macromolecule may frequently become …