Machine intelligence in peptide therapeutics: A next‐generation tool for rapid disease screening
S Basith, B Manavalan, T Hwan Shin… - Medicinal research …, 2020 - Wiley Online Library
Discovery and development of biopeptides are time‐consuming, laborious, and dependent
on various factors. Data‐driven computational methods, especially machine learning (ML) …
on various factors. Data‐driven computational methods, especially machine learning (ML) …
Prediction of bio-sequence modifications and the associations with diseases
C Ao, L Yu, Q Zou - Briefings in Functional Genomics, 2021 - academic.oup.com
Modifications of protein, RNA and DNA play an important role in many biological processes
and are related to some diseases. Therefore, accurate identification and comprehensive …
and are related to some diseases. Therefore, accurate identification and comprehensive …
iLearnPlus: a comprehensive and automated machine-learning platform for nucleic acid and protein sequence analysis, prediction and visualization
Sequence-based analysis and prediction are fundamental bioinformatic tasks that facilitate
understanding of the sequence (-structure)-function paradigm for DNAs, RNAs and proteins …
understanding of the sequence (-structure)-function paradigm for DNAs, RNAs and proteins …
iPro-WAEL: a comprehensive and robust framework for identifying promoters in multiple species
Promoters are consensus DNA sequences located near the transcription start sites and they
play an important role in transcription initiation. Due to their importance in biological …
play an important role in transcription initiation. Due to their importance in biological …
HLPpred-Fuse: improved and robust prediction of hemolytic peptide and its activity by fusing multiple feature representation
Motivation Therapeutic peptides failing at clinical trials could be attributed to their toxicity
profiles like hemolytic activity, which hamper further progress of peptides as drug …
profiles like hemolytic activity, which hamper further progress of peptides as drug …
Meta-i6mA: an interspecies predictor for identifying DNA N6-methyladenine sites of plant genomes by exploiting informative features in an integrative machine …
Abstract DNA N 6-methyladenine (6mA) represents important epigenetic modifications,
which are responsible for various cellular processes. The accurate identification of 6mA sites …
which are responsible for various cellular processes. The accurate identification of 6mA sites …
iUmami-SCM: a novel sequence-based predictor for prediction and analysis of umami peptides using a scoring card method with propensity scores of dipeptides
Umami or the taste of monosodium glutamate represents one of the major attractive taste
modalities in humans. Therefore, knowledge about biophysical and biochemical properties …
modalities in humans. Therefore, knowledge about biophysical and biochemical properties …
Computational prediction and interpretation of cell-specific replication origin sites from multiple eukaryotes by exploiting stacking framework
Origins of replication sites (ORIs), which refers to the initiative locations of genomic DNA
replication, play essential roles in DNA replication process. Detection of ORIs' distribution in …
replication, play essential roles in DNA replication process. Detection of ORIs' distribution in …
iFeatureOmega: an integrative platform for engineering, visualization and analysis of features from molecular sequences, structural and ligand data sets
The rapid accumulation of molecular data motivates development of innovative approaches
to computationally characterize sequences, structures and functions of biological and …
to computationally characterize sequences, structures and functions of biological and …
iDNA-MS: an integrated computational tool for detecting DNA modification sites in multiple genomes
Summary 5hmC, 6mA, and 4mC are three common DNA modifications and are involved in
various of biological processes. Accurate genome-wide identification of these sites is …
various of biological processes. Accurate genome-wide identification of these sites is …