Scopoletin: A review of its source, biosynthesis, methods of extraction, and pharmacological activities

LD Antika, AN Tasfiyati, H Hikmat… - … für Naturforschung C, 2022 - degruyter.com
Scopoletin, also known as 6-methoxy-7 hydroxycoumarin, is one of the naturally occurring
coumarin commonly found in many edible plants and plays an important role in human …

Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades

T Efferth, O Kadioglu, MEM Saeed, EJ Seo… - Phytochemistry …, 2021 - Springer
Multidrug resistance is a major factor causing the failure of cancer chemotherapy. Efflux
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …

Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro/in vivo studies and live-cell imaging

L Herrmann, M Leidenberger, AS de Morais, C Mai… - Chemical …, 2023 - pubs.rsc.org
Malaria is one of our planet's most widespread and deadliest diseases, and there is an ever-
consistent need for new and improved pharmaceuticals. Natural products have been an …

Anticancer activity of natural coumarins for biological targets

A Önder - Studies in natural products chemistry, 2020 - Elsevier
Coumarins are a class of secondary metabolites and naturally occurring benzopyrone
derivatives. Previously, the identification of natural coumarins from natural sources has been …

[PDF][PDF] Scopoletin exerts anticancer effects on human cervical cancer cell lines by triggering apoptosis, cell cycle arrest, inhibition of cell invasion and PI3K/AKT …

Q Tian, L Wang, X Sun, F Zeng, Q Pan, M Xue - J BUON, 2019 - jbuon.com
Purpose: Cervical cancer causes considerable mortality in women world over and the
current treatment options create severe adverse effects. Hence, there is an urgent need to …

Scopoletin: anticancer potential and mechanism of action

L Meilawati, RM Dewi, AN Tasfiyati… - Asian Pacific Journal …, 2023 - journals.lww.com
Cancer is considered a leading cause of death worldwide due to its high morbidity and
mortality rate. Conventional treatments for cancer therapy, such as chemotherapy, and …

Anticancer natural coumarins as lead compounds for the discovery of new drugs

DCGA Pinto, A Silva - Current topics in medicinal chemistry, 2017 - ingentaconnect.com
Cancer is one of the most serious illnesses of our civilization. The International Agency for
Research on Cancer estimated that 14.1 million new cancer cases have been diagnosed …

Valorization of European Cranberry Bush (Viburnum opulus L.) Berry Pomace Extracts Isolated with Pressurized Ethanol and Water by Assessing Their …

L Dienaitė, M Pukalskienė, CV Pereira, AA Matias… - Foods, 2020 - mdpi.com
Defatted by supercritical CO2, Viburnum opulus berry pomace (VOP) was subjected to
consecutive extraction with pressurized ethanol (E) and water (W) and yielded 23% of VOP …

Scopoletin: a review of its pharmacology, pharmacokinetics, and toxicity

XY Gao, XY Li, CY Zhang, CY Bai - Frontiers in Pharmacology, 2024 - frontiersin.org
Scopoletin is a coumarin synthesized by diverse medicinal and edible plants, which plays a
vital role as a therapeutic and chemopreventive agent in the treatment of a variety of …

The Pharmacological Effects and Pharmacokinetics of Active Compounds of Artemisia capillaris

TP Hsueh, WL Lin, JW Dalley, TH Tsai - Biomedicines, 2021 - mdpi.com
Artemisia capillaris Thunb.(A. capillaris, Yin-Chen in Chinese) is a traditional medicinal herb
with a wide spectrum of pharmacological properties ranging from effects against liver …