Hepatitis B has become one of the major global health threats, especially in developing
countries and regions. Hepatitis B virus infection greatly increases the risk for liver diseases …

Hepatitis B virus (HBV) is a hepatotropic virus, which damage to hepatocytes is not direct,
but through the immune system. HBV specific CD4+ T cells can induce HBV specific B cells …

Background & Aims With or without antiviral treatment, few individuals achieve sustained
functional cure of chronic hepatitis B virus (HBV) infection. A better definition of what …

Chronic hepatitis B (CHB) remains a major public health problem worldwide, with limited
treatment options, but inducing an antiviral response by innate immunity activation may …

Background A study of the current situation and characteristics of hepatitis B virus (HBV)
infection among Chinese pregnant women is meaningful to provide baseline information for …

It was extensively recognized that central tolerance to HBV exists in HBs-transgenic (Tg)
mice, however, the immune response to HBV vaccine may be inspired in adult HBs-Tg mice …

Hepatitis B virus (HBV) infection is a global public health problem that is closely related to
liver cirrhosis and hepatocellular carcinoma (HCC). The prevalence of acute and chronic …

Chronic hepatitis B viral (HBV) infection is a major global public health risk that threatens
human life and health, although reaching and vaccinating people have increased. The …

T cells play an important role in the clearance of hepatotropic viruses but may also cause
liver injury and contribute to disease progression in chronic hepatitis B and C virus infections …

Hepatocytes exert pivotal roles in metabolism, protein synthesis and detoxification. Non-
parenchymal liver cells (NPCs), largely comprising macrophages, dendritic cells, hepatic …