Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …

Feature selection technique is a knowledge discovery tool which provides an understanding
of the problem through the analysis of the most relevant features. Feature selection aims at …

Current research on imbalanced data recognises that class imbalance is aggravated by
other data intrinsic characteristics, among which class overlap stands out as one of the most …

Drug discovery is important in cancer therapy and precision medicines. Traditional
approaches of drug discovery are mainly based on in vivo animal experiments and in vitro …

Background The application of computational and multi-omics approaches has aided our
understanding of carcinogenesis and the development of therapeutic strategies …

Esophageal adenocarcinoma (EAC) is a deadly cancer with high mortality rate, especially in
economically advanced countries, while Barrett's esophagus (BE) is reported to be a …

Alzheimer's disease (AD) is the most frequent cause of neurodegenerative dementia and
affects nearly 50 million people worldwide. Early stage diagnosis of AD is challenging, and …

Breast cancer is the most common cause of death in women worldwide. Approximately 5%–
10% of instances are attributed to mutations acquired from the parents. Therefore, it is highly …

Aurora kinase (AURK) is a normal cell proliferation-inducing enzyme encoded by AURK
gene in humans. It belongs to the family of serine/threonine kinase. Based on its function …

Background Pretreatment individualized assessment of tumor response to induction
chemotherapy (ICT) is a need in locoregionally advanced nasopharyngeal carcinoma …