The physiological stress response is responsible for the maintenance of homeostasis in the
presence of real or perceived challenges. In this function, the brain activates adaptive …

The neurohypophysial hormone arginine vasopressin (AVP) is essential for a wide range of
physiological functions, including water reabsorption, cardiovascular homeostasis, hormone …

Since corticotropin-releasing factor (CRF) was first characterized, a growing family of ligands
and receptors has evolved. The mammalian family members include CRF, urocortinI (UcnI) …

Exposure to hostile conditions initiates responses organized to enhance the probability of
survival. These coordinated responses, known as stress responses, are composed of …

Highlights•Chronic stress increases the risk of cardiometabolic disease.•CRH and
catecholamines integrate anorexigenic-like responses to stress.•Glucocorticoids and NPY …

Mammals respond to challenging situations with characteristic changes in their behaviour as
well as in autonomic and neuroendocrine parameters aimed at reinstating their disturbed …

One hallmark of psychiatric conditions is the vast continuum of individual differences in
susceptibility vs. resilience resulting from the interaction of genetic and environmental …

Corticotropin-releasing factor (CRF) and its related family members are implicated in stress-
related disorders such as anxiety and depression. Recently, two new members of this …

Corticotropin-releasing hormone (CRH) is centrally involved in coordinating responses to a
variety of stress-associated stimuli. Recent clinical data implicate CRH in the …

Depression is accompanied by an array of neurobiological variations, including altered HPA
axis activity, monoamine, growth factor and inflammatory immune functioning. In addition, a …