[HTML][HTML] The roles of liver-resident lymphocytes in liver diseases

Y Wang, C Zhang - Frontiers in immunology, 2019 - frontiersin.org
Tissue-resident lymphocytes usually reside in barrier sites and are involved in innate and
adaptive immunity. In recent years, many studies have shown that multiple types of …

[HTML][HTML] Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases

JH Ellwanger, B Kulmann-Leal, V de Lima Kaminski… - Virus research, 2020 - Elsevier
The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …

[HTML][HTML] Th17 cells inhibit CD8+ T cell migration by systematically downregulating CXCR3 expression via IL-17A/STAT3 in advanced-stage colorectal cancer patients

D Wang, W Yu, J Lian, Q Wu, S Liu, L Yang, F Li… - Journal of hematology & …, 2020 - Springer
Background CD8+ T cell trafficking to the tumor site is essential for effective colorectal
cancer (CRC) immunotherapy. However, the mechanism underlying CD8+ T cell infiltration …

[HTML][HTML] Tissue-resident memory T cells in chronic liver diseases: Phenotype, development and function

Y Li, Z You, R Tang, X Ma - Frontiers in Immunology, 2022 - frontiersin.org
Tissue-resident memory (TRM) T cells are a unique subset of memory T cells that are critical
for the first line of defense against pathogens or antigens in peripheral non-lymphoid tissues …

[HTML][HTML] Immunomodulation of CXCL10 secretion by hepatitis C virus: could CXCL10 be a prognostic marker of chronic hepatitis C?

SM Ferrari, P Fallahi, I Ruffilli, G Elia… - Journal of immunology …, 2019 - hindawi.com
Chemokine (CXC motif) ligand (CXCL) 10 and other CXCR3 chemokines are involved in the
pathogenesis of acute and “chronic hepatitis C virus (HCV) infection”(CHC). Here, we review …

[HTML][HTML] Induction of antigen specific intrahepatic CD8+ T cell responses by a secreted heat shock protein based gp96-Ig-PfCA malaria vaccine

L Padula, E Fisher, W Wijayalath, NB Patterson… - Frontiers in …, 2023 - frontiersin.org
Introduction A highly efficacious and durable vaccine against malaria is an essential tool for
global malaria eradication. One of the promising strategies to develop such a vaccine is to …

Jigsaw falling into place: A review and perspective of lymphoid tissue CD8+ T cells and control of HIV

S Nguyen, A Sada-Japp, C Petrovas, MR Betts - Molecular immunology, 2020 - Elsevier
CD8+ T cells are crucial for immunity against viral infections, including HIV. Several
characteristics of CD8+ T cells, such as polyfunctionality and cytotoxicity, have been …

Single-dose vaccination with a hepatotropic adeno-associated virus efficiently localizes T cell immunity in the liver with the potential to confer rapid protection against …

ZA Mekonnen, B Grubor-Bauk, K English… - Journal of …, 2019 - Am Soc Microbiol
Hepatitis C virus (HCV) is a significant contributor to the global disease burden, and
development of an effective vaccine is required to eliminate HCV infections worldwide …

[HTML][HTML] Virus–Host Protein Interaction Network of the Hepatitis E Virus ORF2-4 by Mammalian Two-Hybrid Assays

L Corneillie, I Lemmens, K Weening, A De Meyer… - Viruses, 2023 - mdpi.com
Throughout their life cycle, viruses interact with cellular host factors, thereby influencing
propagation, host range, cell tropism and pathogenesis. The hepatitis E virus (HEV) is an …

[HTML][HTML] Liver stiffness hinders normalization of systemic inflammation and endothelial activation after hepatitis C virus (HCV) eradication in HIV/HCV coinfected …

B Álvarez, C Restrepo, M García, MA Navarrete-Muñoz… - Vaccines, 2020 - mdpi.com
Systemic inflammation, endothelial dysfunction and coagulopathy are of high clinical
relevance in the management of people living with HIV (PLWH), and even more in patients …