Inhibitory effects of Semaphorin 3F as an alternative candidate to anti-VEGF monoclonal antibody on angiogenesis

G Tan - In Vitro Cellular & Developmental Biology-Animal, 2019 - Springer
Vascular endothelial growth factor (VEGF) inhibition forms the basis for anti-angiogenic
therapies. With the methods based on the monoclonal antibody-mediated typical VEGF …

Semaphorins in the immune system

S Nojima, A Kumanogoh - … : A Diversity of Emerging Physiological and …, 2015 - Springer
Although semaphorins were originally identified as axon-guidance molecules that function
during neuronal development, several semaphorins play a crucial role in various phases of …

Semaphorin 3A levels in vascular and nonvascular phenotypes in systemic sclerosis

M Kayaalp, A Erden, H Apaydin, SC Güven… - Laboratory …, 2023 - academic.oup.com
Abstract Objective Semaphorin 3A (Sema3A) plays a regulatory role in immune responses.
The aim of this study was to evaluate Sema3A levels in patients with systemic sclerosis …

Correlation of peritumoral edema and microvessel density with tissue expression of VEGF, semaphorins 3A and 3C in patients with meningioma

M Salimi-Sotoodeh, A Saffarian, M Taghipour… - Asian Pacific Journal of …, 2018 - waocp.com
Background: Several angiogenic factors correlate with angiogenesis in meningioma while
their exact role is yet to be identified. Semaphorins are described with a variety of …

The Role of Semaphorins and their Receptors in the Immune System and their Relation to Multiple Sclerosis

R Lotfi, K Yari - The Neuroscience Journal of Shefaye Khatam, 2018 - shefayekhatam.ir
Introduction: Semaphorins are large family of secretory and membrane-bound proteins that
first were recognized in the nervous system as axon guidance molecules. Semaphorins …

[引用][C] Semaphorin 家族与胶质瘤

张海东, 张伟, 王回, 朱广廷 - 国际肿瘤学杂志, 2016

SEMA3B 基因真核表达载体的构建及对肺癌细胞恶性生物学行为的影响

赵俊, 何爽, 郑云, 陈敏, 明凯华 - 广州医药, 2015 - gzyyzz.cn
目的构建抑癌基因SEMA3B 真核表达载体pcDNA3. 1-SEMA3B, 并检测其对肺癌A549
细胞恶性生物学行为的影响. 方法应用PCR 扩增SEMA3B 全长cDNA 片段, 构建真核表达载体 …

Characterization of semaphorin 6A-mediated effects on angiogenesis through regulation of VEGF signaling

H Ohnuki, G Tosato - Semaphorin Signaling: Methods and Protocols, 2017 - Springer
Angiogenesis identifies the process of endothelial cell sprouting and remodeling leading to
the formation of new and functional blood vessels. Vascular expansion during development …

Resolving the Interactions between Class 3 Semaphorin Receptors in Live Cells

SM Christie, J Hao, E Tracy, M Buck, JS Yu, AW Smith - bioRxiv, 2021 - biorxiv.org
The plexin/neuropilin/semaphorin family of proteins is involved with tissue patterning in the
developing embryo. These proteins play roles in cell migration and adhesion, but are also …

Plexin-A2 Promotes The Proliferation And The Development Of Tumors From Glioblastoma Derived Cells

S Toledano, AD Sabag, T liburkin-Dan, O Kessler… - bioRxiv, 2021 - biorxiv.org
The semaphorin guidance factors receptor Plexin-A2 transduces sema6A and sema6B
signals and when associated with neuropilins can also transduce sema3C signals. Inhibition …