Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …

Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Purpose The aim of the 2016 quantitative susceptibility mapping (QSM) reconstruction
challenge was to test the ability of various QSM algorithms to recover the underlying …

Ferroptosis is a kind of regulatory cell death (RCD) caused by iron accumulation and lipid
peroxidation, which is characterized by mitochondrial morphological changes and has a …

Since its technical development in the early 1980s, magnetic resonance imaging (MRI) has
quickly been adopted as an essential tool in supporting the diagnosis, longitudinal …

This article provides recommendations for implementing QSM for clinical brain research. It is
a consensus of the International Society of Magnetic Resonance in Medicine, Electro …

Quantitative susceptibility mapping (QSM) is an MR technique that depicts and quantifies
magnetic susceptibility sources. Mapping iron, the dominant susceptibility source in the …

Purpose To study deep gray matter susceptibility in multiple sclerosis (MS) by using
quantitative susceptibility mapping (QSM) and to assess the relationship between …

Traumatic brain injury (TBI) consists of acute and long-term pathophysiological sequelae
that ultimately lead to cognitive and motor function deficits, with age being a critical risk …

Measuring iron content has practical clinical indications in the study of diseases such as
Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as …