[HTML][HTML] Peptide-based positron emission tomography probes: Current strategies for synthesis and radiolabelling

M Failla, G Floresta, V Abbate - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
In medical imaging, techniques such as magnetic resonance imaging, contrast-enhanced
computerized tomography, and positron emission tomography (PET) are extensively …

Effective Treatment of SSTR2-Positive Small Cell Lung Cancer Using 211At-Containing Targeted α-Particle Therapy Agent Which Promotes Endogenous Antitumor …

S Qin, Y Yang, J Zhang, Y Yin, W Liu… - Molecular …, 2023 - ACS Publications
Small cell lung cancer (SCLC) is a neuroendocrine tumor with a high degree of malignancy.
Due to limited treatment options, patients with SCLC have a poor prognosis. We have found …

Quantitative PET tracking of intra-articularly administered 89Zr-peptide-decorated nanoemulsions

S Díez-Villares, L García-Varela… - Journal of Controlled …, 2023 - Elsevier
Intra-articular (IA) administration of drugs for the treatment of diseases such as rheumatoid
arthritis, osteoarthritis and psoriatic arthritis is a common strategy; however, the rapid …

Recent Advances of Anticancer Studies Based on Nano‐Fluorescent Metal‐Organic Frameworks

R Liang, N Liu, F Li - ChemMedChem, 2022 - Wiley Online Library
Nano‐fluorescent metal‐organic frameworks (NF‐MOFs), a kind of newly emerged nano‐
scaled platform, can provide visual, rapid, and highly sensitive optical imaging of cancer …

Dual targeting of DR5 and VEGFR2 molecular pathways by multivalent fusion protein significantly suppresses tumor growth and angiogenesis

AA Isakova, AA Artykov, EA Plotnikova… - International Journal of …, 2024 - Elsevier
Destroying tumor vasculature is a relevant therapeutic strategy due to its involvement in
tumor progression. However, adaptive resistance to approved antiangiogenic drugs …

[HTML][HTML] Exploring the Potential of Zirconium-89 in Diagnostic Radiopharmaceutical Applications: An Analytical Investigation

AMA Mostafa, HMH Zakaly, SAM Issa, MAM Uosif… - Biomedicines, 2023 - mdpi.com
This study highlights the use of 89Zr-oxalate in diagnostic applications with the help of
WinAct and IDAC2. 1 software. It presents the biodistribution of the drug in various organs …

Preclinical evaluation of a dual-receptor targeted tracer [68Ga]Ga-HX01 in 10 different subcutaneous and orthotopic tumor models

X Lv, X Song, Y Long, D Zeng, X Lan, Y Gai - European Journal of Nuclear …, 2023 - Springer
Purpose The integrin αvβ3 and aminopeptidase N (APN/CD13) play vital roles in the tumor
angiogenesis process. They are highly expressed in a variety of tumor cells and proliferating …

肿瘤特异性多肽探针及其在生物成像中的应用

王博, 蔡向东, 肖建喜 - 化学学报, 2024 - sioc-journal.cn
摘要肿瘤是由细胞, 细胞外基质及微环境等多因素组成的复杂系统, 不同因素在肿瘤的发生和
发展中发挥关键作用. 肿瘤细胞, 细胞外基质及微环境的特异性分析对于肿瘤的精准诊断和靶向 …

Tumor-specific Peptide Probes and the Applications in Bioimaging

W Bo, C Xiangdong, X Jianxi - Acta Chimica Sinica, 2024 - sioc-journal.cn
The tumor is a complex system composed of various elements, encompassing cells,
extracellular matrix, and the tumor microenvironment. Each of these distinct factors plays a …

Introduction to Cancer Genetics and Its Symbiotic Relationship

L Gautam, M Vishwakarma, IL Kanwar… - Synbiotics for the …, 2023 - Springer
Cell annexation is an intrinsic cellular pathway by which cells interact with extracellular
stimuli to draft and constrain the structure of their extracellular matrix to evolve, rebuild, and …