▪ Abstract Therapies for myocardial infarction have historically been developed by trial and
error, rather than from an understanding of the structure and function of the healing infarct …

Since the early studies of Rushmer,'Braun-wald et a1., 2 Hefner et a1., 3 Dodge and
associates, 4-7 Spotnitz et al.,'Laks et al., 9 and Noble et al.” there has been renewed …

To define the relationship between infarct size and ventricular performance, we performed
hemodynamic studies in rats 21 days after left coronary artery occlusion. Ventricular …

A sensitive method was developed for detecting stiffness changes in the left ventricle. Stress-
strain relationships (σ--ε) were obtained in the form dσ/dε= kσ+ c from published studies on …

Ventricular dilatation may have important prognostic implications for the survival of patients
with left ventricular (LV) dysfunction. To determine the manner and extent to which the left …

To determine the effects of healed myocardial infarction on the diastolic compliance of the
left ventricle, we studied 36 rats 26 days after left coronary artery ligation. Peak cardiac …

After myocardial infarction (MI), left ventricular (LV) end-diastolic pressure (EDP) is higher
than mean pulmonary artery wedge pressure because of powerful atrial contraction. To …

The evaluation of left ventricular (LV) compliance by use of the pressure-volume (PV)
relationship encounters several serious difficulties. Since the PV relationship is curvilinear, it …

Hypertrophy after myocardial infarction would be a very important process for compensation
of damaged myocardium and preservation of cardiac function. Fifty-four female Sprague …

The left ventricular (LV) pressure-volume (PV) relationship is a resultant of several
determinants, including initial ventricular volume, geometry, and wall stiffness. A quantitative …