[HTML][HTML] Fungal endophytes: A promising frontier for discovery of novel bioactive compounds

MM Gakuubi, M Munusamy, ZX Liang, SB Ng - Journal of fungi, 2021 - mdpi.com
For years, fungi have served as repositories of bioactive secondary metabolites that form the
backbone of many existing drugs. With the global rise in infections associated with …

[HTML][HTML] Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology

F Fierro, I Vaca, NI Castillo, RO García-Rico, R Chávez - Microorganisms, 2022 - mdpi.com
The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical
advance has ever had the same impact in the clinical practise. The fungus Penicillium …

[HTML][HTML] Comparative genomics reveals the organic acid biosynthesis metabolic pathways among five lactic acid bacterial species isolated from fermented vegetables

CO Okoye, K Dong, Y Wang, L Gao, X Li, Y Wu… - New …, 2022 - Elsevier
Lactic acid bacteria (LAB) comprise a widespread bacterial group, inhabiting the niches of
fermented vegetables and capable of producing beneficial organic acids. In the present …

[HTML][HTML] Fungal BGCs for production of secondary metabolites: main types, central roles in strain improvement, and regulation according to the piano principle

AA Zhgun - International Journal of Molecular Sciences, 2023 - mdpi.com
Filamentous fungi are one of the most important producers of secondary metabolites. Some
of them can have a toxic effect on the human body, leading to diseases. On the other hand …

Transcriptomics and metabolomic profiling identify molecular mechanism for Aspergillus flavus infection in grain

C Ding, T Tian, Q Liu, S Zhao, T Tao, H Wu… - Food Frontiers, 2023 - Wiley Online Library
Aspergillus flavus is a ubiquitous saprophyte and opportunistic fungal pathogen with
worldwide distribution, which causes diseases commonly in agricultural commodities and …

Exploring the regulated effects of solid-state fortified Jiuqu and liquid-state fortified agent on Chinese Baijiu brewing

Y Wang, S Quan, Y Xia, Z Wu, W Zhang - Food Research International, 2024 - Elsevier
Zaopei is the direct source of Chinese liquor (Baijiu). Adding functional strains to Zaopei is a
potential strategy to regulate Baijiu brewing, mainly including the two ways of solid-state …

[HTML][HTML] A comprehensive gene expression profile of pectin degradation enzymes reveals the molecular events during cell wall degradation and pathogenesis of rice …

T Bhaskar Rao, R Chopperla, NB Prathi… - Journal of fungi, 2020 - mdpi.com
Sheath blight disease of rice caused by Rhizoctonia solani Kühn (teleomorph:
Thanatephorus cucumeris) remains a global challenge due to the absence of reliable …

[HTML][HTML] bZIP transcription factors PcYap1 and PcRsmA link oxidative stress response to secondary metabolism and development in Penicillium chrysogenum

WD Pérez-Pérez, U Carrasco-Navarro… - Microbial Cell …, 2022 - Springer
Background Reactive oxygen species (ROS) trigger different morphogenic processes in
filamentous fungi and have been shown to play a role in the regulation of the biosynthesis of …

[HTML][HTML] Identification of key genes involved in secondary metabolite biosynthesis in Digitalis purpurea

F Amiri, A Moghadam, A Tahmasebi, A Niazi - Plos one, 2023 - journals.plos.org
The medicinal plant Digitalis purpurea produces cardiac glycosides that are useful in the
pharmaceutical industry. These bioactive compounds are in high demand due to …

[HTML][HTML] Secondary Metabolites Produced by the Blue-Cheese Ripening Mold Penicillium roqueforti; Biosynthesis and Regulation Mechanisms

R Chávez, I Vaca, C García-Estrada - Journal of Fungi, 2023 - mdpi.com
Filamentous fungi are an important source of natural products. The mold Penicillium
roqueforti, which is well-known for being responsible for the characteristic texture, blue …