pH-responsive polymer nanomaterials for tumor therapy

S Chu, X Shi, Y Tian, F Gao - Frontiers in oncology, 2022 - frontiersin.org
The complexity of the tumor microenvironment presents significant challenges to cancer
therapy, while providing opportunities for targeted drug delivery. Using characteristic signals …

Evaluation of potential inhibitory effects on acetylcholinesterase, pancreatic lipase, and cancer cell lines using raw leaves extracts of three fabaceae species

I Fatima, N Safdar, W Akhtar, A Munir, S Saqib, A Ayaz… - Heliyon, 2023 - cell.com
The present study examined the biological potential and phytochemicals of Sophora mollis,
Mucuna pruriens, and Indigofera atropurpurea methanolic leaf extracts. In vitro anti …

Synergized Toxicity of Promising Plant Extracts and Synthetic Chemicals against Fall Armyworm Spodoptera frugiperda (JE Smith) (Lepidoptera: Noctuidae) in …

KS Ahmed, A Idrees, MZ Majeed, MI Majeed… - Agronomy, 2022 - mdpi.com
Fall armyworm, Spodoptera frugiperda (JE Smith)(Lepidoptera: Noctuidae), is a destructive
pest of a wide array of agricultural and horticultural crops worldwide. This in vitro research …

Chromosomal level genome assembly of medicinal plant Sophora flavescens

Z Qu, W Wang, DL Adelson - Scientific Data, 2023 - nature.com
Sophora flavescens is a medicinal plant in the genus Sophora of the Fabaceae family. The
root of S. flavescens is known in China as Kushen and has a long history of wide use in …

Native American ataxia medicines rescue ataxia-linked mutant potassium channel activity via binding to the voltage sensing domain

RW Manville, J Alfredo Freites, R Sidlow… - Nature …, 2023 - nature.com
There are currently no drugs known to rescue the function of Kv1. 1 voltage-gated potassium
channels carrying loss-of-function sequence variants underlying the inherited movement …

Sophoraflavanone G: A review of the phytochemistry and pharmacology

Y Gao, J Sun, W Li, W Deng, Y Wang, X Li, Z Yang - Fitoterapia, 2024 - Elsevier
Bioactive compounds derived from natural sources have long been investigated for the
prevention and treatment of human diseases. Sophoraflavanone G (SFG), a lavandulyl …

The anti‐inflammatory activity of flavonoids and alkaloids from Sophora flavescens alleviates psoriasiform lesions: Prenylation and methoxylation beneficially …

CF Lin, MH Lin, CF Hung, A Alshetaili… - Phytotherapy …, 2024 - Wiley Online Library
The herb Sophora flavescens displays anti‐inflammatory activity and can provide a source
of antipsoriatic medications. We aimed to evaluate whether S. flavescens extracts and …

Suppression of inflammation-induced lung cancer cells proliferation and metastasis by exiguaflavanone A and exiguaflavanone B from Sophora exigua root extract …

P Arjsri, K Srisawad, W Semmarath… - Frontiers in …, 2023 - frontiersin.org
Objective: Non-small cell lung cancer (NSCLC) is recognized for its aggressive nature and
propensity for high rates of metastasis. The NLRP3 inflammasome pathway plays a vital role …

Investigating the potential anti-SARS-CoV-2 and anti-MERS-CoV activities of yellow necklacepod among three selected medicinal plants: extraction, isolation …

HI Abd-Alla, O Kutkat, HM Sweelam, WM Eldehna… - Metabolites, 2022 - mdpi.com
The anti-MERS-CoV activities of three medicinal plants (Azadirachta indica, Artemisia
judaica, and Sophora tomentosa) were evaluated. The highest viral inhibition percentage …

Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in rats via suppressing oxidative stress and apoptosis

HI Abd-Alla, G Ibrahim Fouad, KA Ahmed, K Shaker - Biomarkers, 2022 - Taylor & Francis
ABSTRACT Introduction Fruits of Ammi majus, commonly called bishop's weed, contain a
significant amount of furanocoumarins. Alloimperatorin (Allo, 6) was isolated from the free …