Rapid progress in human genome decoding has accelerated search for the role of gene
polymorphisms in the pathogenesis of complex multifactorial diseases. This review …

High-density lipoprotein (HDL) particles exhibit multiple antiatherogenic effects. They are
key players in the reverse cholesterol transport which shuttles cholesterol from peripheral …

Background: The APOE gene and its protein product is associated with a number of plasma
proteins like very-low density lipoprotein (VLDL), high density lipoprotein (HDL) …

Apolipoprotein E (APOE) is thought to be responsible for the transportation of lipids within
the brain, maintaining structural integrity of the microtubule within the neurone, and assisting …

OBJECTIVE The potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1)
has been found through a genome-wide association study to be a strong candidate for …

Several polymorphisms in apolipoprotein A1 (APOA1) gene have been associated with
metabolic diseases. Increased transcription efficiency was observed in− 75A allele carriers …

Many studies have shown that the prevalence and onset of coronary heart disease (CHD) is
sex-dependent. CHD prevalence is lower in women than in men at all ages. Furthermore …

Сердечнососудистые заболевания, несмотря на современные технологии диагностики
и лечения, продолжают лидировать по распространенности, инвалидизации и …

Associations of polymorphisms in the angiotensin I‐converting enzyme (ACE),
apolipoprotein B (APOB) and apolipoprotein E (APOE) genes with hypertension and …

Objective—To identify common variations in genes in the reverse cholesterol transport
pathway with nongender-specific influence on plasma lipid and apolipoprotein levels …