Modulation of renal insulin signaling pathway and antioxidant enzymes with streptozotocin-induced diabetes: effects of resveratrol

G Sadi, G Şahin, A Bostanci - Medicina, 2018 - mdpi.com
Background and objectives: Diabetes mellitus is a disease of insulin deficiency or its inability
of usage by the target tissues leading to impairment of carbohydrate, lipid, and protein …

[HTML][HTML] Crocin mitigates carbon tetrachloride-induced liver toxicity in rats

S Bahashwan, MH Hassan, H Aly, MM Ghobara… - Journal of Taibah …, 2015 - Elsevier
Abstract Objectives Carbon tetrachloride (CCl4) is one of the most dangerous hepatotoxic
environmental pollutants thus this study aimed at investigating the potential preventive effect …

Resveratrol mitigates pancreatic TF activation and autophagy-mediated beta cell death via inhibition of CXCL16/ox-LDL pathway: A novel protective mechanism …

MA Darwish, MS Abdel-Bakky, BAS Messiha… - European journal of …, 2021 - Elsevier
The role of CXC chemokine ligand 16 (CXCL16), oxidized LDL (ox-LDL), tissue factor (TF)
and autophagy-induced beta cell death in type 1 diabetes mellitus (T1DM) pathogenesis is …

[HTML][HTML] Targeting sirtuins for the treatment of diabetes

FK Huynh, KA Hershberger… - Diabetes management …, 2013 - ncbi.nlm.nih.gov
Sirtuins are a class of NAD+-dependent deacetylases, such as deacetylases, that have a
wide array of biological functions. Recent studies have suggested that reduced sirtuin action …

Oral health, diabetes, and body weight

LTA Cintra, RO Samuel, AKC Prieto, DH Sumida… - Archives of oral …, 2017 - Elsevier
Objectives The effects of apical periodontitis (AP) and periodontal disease (PD) on organ
weights in rats with diabetes mellitus (DM) were evaluated. Design Eighty male rats (Rattus …

Cardiac energy metabolism and oxidative stress biomarkers in diabetic rat treated with resveratrol

K Carolo dos Santos, C Pereira Braga… - PLoS …, 2014 - journals.plos.org
Resveratrol (RSV), polyphenol from grape, was studied to evaluate its effects on calorimetric
parameters, energy metabolism, and antioxidants in the myocardium of diabetic rats. The …

A comparative study between curcumin and curcumin nanoemulsion on high-fat, high-fructose diet-induced impaired spermatogenesis in rats

M Nasr, H Abd-Allah, OAH Ahmed-Farid… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives Curcumin is a promising nutraceutical with reported diverse therapeutic
properties, but of limited oral bioavailability. The current manuscript investigates the role of …

[PDF][PDF] Phytoalexins: defend systems of plants and pharmacological potential—a systematic review

T Sivakumar, B Deepa - Int J Eng Technol Manag Sci, 2023 - researchgate.net
Plants are easily prone towards microbial infections on exposure to microorganisms and
pathogens. In order to defense, plants produce low molecular weight secondary metabolites …

Hypoglycemic and antioxidant effects of Hibiscus rosa-sinensis L. leaves extract on liver and kidney damage in streptozotocin induced diabetic rats

LH Zaki, SM Mohamed, SAE Bashandy… - African Journal of …, 2017 - academicjournals.org
Hibiscus is commonly used traditionally for the treatment of some diseases such as
hypertension and as antidiabetic herbal medicine. The objective of the present study is to …

[PDF][PDF] Effects of metformin plus gliclazide versus metformin plus glimepiride on cardiovascular risk factors in patients with type 2 diabetes mellitus.

MH Hassan, GM Abd-Allah - Pakistan Journal of …, 2015 - pdfs.semanticscholar.org
High blood glucose level, lipid profile disturbances and plasma homocysteine (Hcy) are
important risk factors for cardiovascular diseases in patients with type 2 diabetes. This study …