The concept of older people becoming frail is not a new one. The ability to define frailty in a
clinically meaningful manner has remained elusive, however. Frailty can be considered to …

ABSTRACT Background/Aims Myostatin belongs to the transforming growth factor‐β
superfamily and negatively regulates skeletal muscle mass. Its deletion induces muscle …

The gain in muscle mass as a result of resistance training is dependent on changes in both
anabolic and catabolic reactions. A frequency of two to three exercise sessions per week is …

There is now a large body of evidence that weight loss in older persons not only increases
mortality, but also increases the incidence of hip fracture, functional deterioration and …

Myostatin is a member of the transforming growth factor β superfamily of secreted growth
factors that negatively regulates skeletal muscle size. Mice null for the myostatin gene have …

Myogenesis is controlled by an elaborate system of extrinsic and intrinsic regulatory
mechanisms in all development stages. The aim of this review is to provide an overview of …

Skeletal muscle possesses a high plasticity and a remarkable regenerative capacity that
relies mainly on muscle stem cells (MuSCs). Molecular and cellular components of the …

MicroRNAs are a class of recently discovered small RNA molecules that regulate other
genes in the human genome. Studies in human cells and model organisms have begun to …

Abstract Wilborn, CD, Taylor, LW, Greenwood, M, Kreider, RB, and Willoughby, DS. Effects
of different intensities of resistance exercise on regulators of myogenesis. J Strength Cond …

Skeletal muscle has multiple functions and is a key component of the locomotor system. It
consists of carbohydrates and amino acids for different tissues such as skin, heart and brain …