Ophthalmologic manifestations of primary Sjögren's syndrome

AM Roszkowska, GW Oliverio, E Aragona, L Inferrera… - Genes, 2021 - mdpi.com
Sjögren's syndrome (SS) is a chronic, progressive, inflammatory, autoimmune disease,
characterized by the lymphocyte infiltration of exocrine glands, especially the lacrimal and …

[HTML][HTML] Management of Sjögren's syndrome: present issues and future perspectives

C Vitali, A Minniti, F Pignataro, W Maglione… - Frontiers in …, 2021 - frontiersin.org
In view of the new possibilities for the treatment of primary Sjögren's syndrome (pSS) given
by the availability of new biotechnological agents targeting the various molecular and …

[HTML][HTML] T cell exosome–derived miR-142-3p impairs glandular cell function in Sjögren's syndrome

J Cortes-Troncoso, SI Jang, P Perez, J Hidalgo… - JCI insight, 2020 - ncbi.nlm.nih.gov
Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly affects exocrine
salivary and lacrimal glands. Local inflammation in the glands is thought to trigger glandular …

Identification of novel genes associated with dysregulation of B cells in patients with primary Sjögren's syndrome

J Inamo, K Suzuki, M Takeshita, Y Kassai… - Arthritis Research & …, 2020 - Springer
Background The aim of this study was to identify the molecular mechanism of dysregulation
of B cell subpopulations of primary Sjögren's syndrome (pSS) at the transcriptome level …

[PDF][PDF] One year in review 2021: Sjögren's syndrome

G Cafaro, R Bursi, LG Chatzis, G Fulvio… - Clin Exp …, 2021 - clinexprheumatol.org
Sjögren's syndrome (SS) is a multifactorial systemic autoimmune disease of unknown
aetiology characterised by a wide spectrum of different clinical manifestations and scattered …

[PDF][PDF] Pathogenesis of primary Sjögren's syndrome beyond B lymphocytes

S Fasano, D Mauro, F Macaluso, F Xiao… - Clin Exp …, 2020 - clinexprheumatol.org
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine
glands of the body, prevalently lacrimal and salivary glands. The pSS pathogenesis has …

SMADS-mediate molecular mechanisms in Sjögren's syndrome

M Sisto, D Ribatti, S Lisi - International Journal of Molecular Sciences, 2021 - mdpi.com
There is considerable interest in delineating the molecular mechanisms of action of
transforming growth factor-β (TGF-β), considered as central player in a plethora of human …

Protective effects of miR‑155‑5p silencing on IFN‑γ‑induced apoptosis and inflammation in salivary gland epithelial cells

J Zhang, L Zhu, H Shi, H Zheng - Experimental and …, 2021 - spandidos-publications.com
Previous studies have demonstrated that microRNAs (miRNAs/miRs) serve a vital role in the
pathogenesis of Sjögren's syndrome (SS). The present study aimed to investigate the role of …

Exosome-derived microRNAs from mouthrinse have the potential to be novel biomarkers for Sjögren syndrome

K Yamashiro, T Hamada, K Mori, K Nishi… - Journal of Personalized …, 2022 - mdpi.com
Sjögren syndrome (SS) is diagnosed based on invasive tissue biopsies and blood sampling.
Therefore, a novel non-invasive and simple inspection diagnostic marker of SS is required …

Long non-coding RNAs modulate Sjögren's syndrome associated gene expression and are involved in the pathogenesis of the disease

M Dolcino, E Tinazzi, C Vitali, N Del Papa… - Journal of Clinical …, 2019 - mdpi.com
Primary Sjögren's syndrome (pSjS) is a chronic systemic autoimmune disorder, primarily
affecting exocrine glands; its pathogenesis is still unclear. Long non-coding RNAs …