The emerging antioxidant paradigm of mesenchymal stem cell therapy

R Stavely, K Nurgali - Stem Cells Translational Medicine, 2020 - academic.oup.com
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for
the treatment of diverse diseases, with many promising outcomes achieved in animal …

The anti-inflammatory properties of mesenchymal stem cells in epilepsy: Possible treatments and future perspectives

V Salari, F Mengoni, F Del Gallo, G Bertini… - International Journal of …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent adult cells with self-renewing capacities.
MSCs display specific properties, such as the ability to repair damaged tissues, resulting in …

Gene and cell therapy for epilepsy: a mini review

AA Shaimardanova, DS Chulpanova… - Frontiers in Molecular …, 2022 - frontiersin.org
Epilepsy is a chronic non-infectious disease of the brain, characterized primarily by recurrent
unprovoked seizures, defined as an episode of disturbance of motor, sensory, autonomic, or …

Stem-cell-based therapy: the celestial weapon against neurological disorders

MA Zayed, S Sultan, HO Alsaab, SM Yousof, GI Alrefaei… - Cells, 2022 - mdpi.com
Stem cells are a versatile source for cell therapy. Their use is particularly significant for the
treatment of neurological disorders for which no definitive conventional medical treatment is …

Therapeutic potential of mesenchymal stem cells in the treatment of epilepsy and their interaction with antiseizure medications

MR Tesiye, M Gol, MR Fadardi, SNM Kani, AM Costa… - Cells, 2022 - mdpi.com
Epilepsy is a life-threatening neurological disease that affects approximately 70 million
people worldwide. Although the vast majority of patients may be successfully managed with …

[HTML][HTML] Plant-mediated green synthesis of gold nanoparticles using an aqueous extract of Passiflora ligularis, optimization, characterizations, and their …

NS Al-Radadi, WM Al-Bishri, NA Salem… - Saudi Pharmaceutical …, 2024 - Elsevier
The current study was conducted to examine an innovative method for synthesizing gold
nanoparticles (AuNPs) from an aqueous sweet granadilla (Passiflora ligularis Juss) P …

Metformin ameliorates the status epilepticus-induced hippocampal pathology through possible mTOR modulation

SL Bojja, B Medhi, S Anand, A Bhatia, R Joshi… - …, 2021 - Springer
The initial precipitating injury such as SE progresses to chronic epilepsy through multiple
epileptogenic processes. Early epileptogenic events are generally characterized by …

Potential Plausible Role of Stem Cell for Treating Depressive Disorder: A Retrospective Review

Z Chang, Q Wang, L Li, B Jiang, X Zhou, H Zhu… - Molecular …, 2023 - Springer
Depression poses a significant threat to global physical and mental health, impacting
around 3.8% of the population with a rising incidence. Current treatment options primarily …

Mesenchymal stem cell therapy for focal epilepsy: A systematic review of preclinical models and clinical studies

A Ramos‐Fresnedo, C Perez‐Vega, RA Domingo… - …, 2022 - Wiley Online Library
Drug‐resistant epilepsy (DRE) is characterized by recurrent seizures despite appropriate
treatment with antiseizure medication (ASM). Due to their regenerative and …

Ameliorating effect of umbilical cord mesenchymal stem cells in a human induced pluripotent stem cell model of Dravet syndrome

H Zhao, S Li, L He, F Tang, X Han, W Deng, Z Lin… - Molecular …, 2022 - Springer
Dravet syndrome (DS) is a form of severe childhood-onset refractory epilepsy typically
caused by a heterozygous loss-of-function mutation. DS patient-derived induced pluripotent …