Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …

Latent Mycobacterium tuberculosis Infection | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Better understanding of the immunological components and their interactions necessary to
prevent or control Mycobacterium tuberculosis (Mtb) infection in humans is critical for …

Biomarkers are indispensable to the development of new tuberculosis therapeutics and
vaccines. The most robust biomarkers measure factors that are essential to the underlying …

Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB).
Although the tuberculin skin test and interferon-gamma release assay can be used to …

There is an urgent need for new and better vaccines against tuberculosis (TB). Current
vaccine design strategies are generally focused on the enhancement of cell-mediated …

Despite wide antiretroviral scale-up during the past two decades resulting in declining new
infections and mortality globally, HIV-associated tuberculosis remains as a major public …

Tuberculosis (TB) remains a leading cause of human suffering and mortality despite
decades of effective treatment being available. Accurate and timely diagnosis remains an …

Tuberculosis infection (TBI) is defined as a state of infection in which individuals host live
Mycobacterium tuberculosis with or without clinical signs of active TB. It is now understood …

The accurate diagnosis of tuberculosis (TB) in children remains challenging. A myriad of
common childhood diseases can present with similar symptoms and signs, and …