The repurposing of non-peptide neurokinin-1 receptor antagonists as antitumor drugs: An urgent challenge for aprepitant
R Coveñas, FD Rodríguez, P Robinson… - International journal of …, 2023 - mdpi.com
The substance P (SP)/neurokinin-1 receptor (NK-1R) system is involved in cancer
progression. NK-1R, activated by SP, promotes tumor cell proliferation and migration …
progression. NK-1R, activated by SP, promotes tumor cell proliferation and migration …
Role of Cannabinoids in Oral Cancer
B Cretu, A Zamfir, S Bucurica, AE Scheau… - International Journal of …, 2024 - mdpi.com
Cannabinoids have incited scientific interest in different conditions, including malignancy,
due to increased exposure to cannabis. Furthermore, cannabinoids are increasingly used to …
due to increased exposure to cannabis. Furthermore, cannabinoids are increasingly used to …
The interaction mechanism of candidone with calf thymus DNA: A multi-spectroscopic and MD simulation study
In this investigation, the effects of candidone on the structure and conformation of DNA were
evaluated by spectroscopic methods, molecular dynamics simulation, and molecular …
evaluated by spectroscopic methods, molecular dynamics simulation, and molecular …
Investigating the effect of pH on the interaction of cypermethrin with human serum albumin: Insights from spectroscopic and molecular dynamics simulation studies
To efficiently combat the negative consequences of the utilization of pesticides and
hazardous substances with biomolecules, it is crucial to comprehend the features of the …
hazardous substances with biomolecules, it is crucial to comprehend the features of the …
Combined effect of plasma-activated water and topotecan in glioblastoma cells
Simple Summary New forms of cancer treatment are needed to target resistant cancers or
reduce severe side effects associated with some treatments. Cold Atmospheric Plasma …
reduce severe side effects associated with some treatments. Cold Atmospheric Plasma …
Interaction between the antioxidant compound safranal and α-chymotrypsin in spectroscopic fields and molecular modeling approaches
S Zohreh Vahedi, S Farhadian, B Shareghi… - Journal of …, 2024 - Taylor & Francis
Among various herbal plants, saffron has been the subject of study in various medical and
food fields. Among the compounds of saffron, safranal is one of them. Safranal is a …
food fields. Among the compounds of saffron, safranal is one of them. Safranal is a …
Effect of folic acid‐linked chitosan‐coated PLGA‐based curcumin nanoparticles on the redox system of glioblastoma cancer cells
N Ghoreyshi, A Ghahremanloo, H Javid… - Phytochemical …, 2023 - Wiley Online Library
Objectives Oxidative stress is one of the carcinogenic mechanisms underlying the
development of glioblastoma multiforme (GBM), a highly aggressive brain tumor type …
development of glioblastoma multiforme (GBM), a highly aggressive brain tumor type …
The Role of Silymarin in Mitigating Inflammation and Cognitive Impairment Induced by Ovariectomy in Wistar Rats
Background. Silymarin, a polyphenolic flavonoid found in milk thistle, has been used to treat
liver and brain injuries in humans and animals. The study aims to investigate the protective …
liver and brain injuries in humans and animals. The study aims to investigate the protective …
Glioblastoma, an opportunity T cell trafficking could bring for the treatment
M Karimi-Shahri, M Khorramdel, S Zarei… - Molecular Biology …, 2022 - Springer
Purpose Infiltrating into the vital structure of the brain, located in the inaccessible anatomical
region, and having molecular heterogeneity, glioblastoma (GBM)–with no doubt–is one of …
region, and having molecular heterogeneity, glioblastoma (GBM)–with no doubt–is one of …
Shake It Up Baby Now: The Changing Focus on TWIST1 and Epithelial to Mesenchymal Transition in Cancer and Other Diseases
D Mirjat, M Kashif, CM Roberts - International Journal of Molecular …, 2023 - mdpi.com
TWIST1 is a transcription factor that is necessary for healthy neural crest migration,
mesoderm development, and gastrulation. It functions as a key regulator of epithelial-to …
mesoderm development, and gastrulation. It functions as a key regulator of epithelial-to …