[HTML][HTML] G-Protein-Coupled receptors in rheumatoid arthritis: Recent insights into mechanisms and functional roles

J Zhao, K Wei, P Jiang, C Chang, L Xu, L Xu… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to joint damage and
even disability. Although there are various clinical therapies for RA, some patients still have …

Peptide Vaccines as Therapeutic and Prophylactic Agents for Female-Specific Cancers: The Current Landscape

M Lekshmy, CR Dhanya, JSK Smrithi, JA Sindhurani… - Pharmaceuticals, 2023 - mdpi.com
Breast and gynecologic cancers are significant global threats to women's health and those
living with the disease require lifelong physical, financial, and social support from their …

Epitope Mapping of an Anti-Mouse CXCR6 Monoclonal Antibody (Cx6Mab-1) Using the 2 × Alanine Scanning Method

Y Isoda, T Tanaka, H Suzuki, T Asano… - Monoclonal …, 2022 - liebertpub.com
The CXC chemokine receptor 6 (CXCR6) is a member of the G protein-coupled receptor
family that is highly expressed in helper T type 1 cells, cytotoxic T lymphocytes (CTLs), and …

Epitope Mapping of the Novel Anti-Human CCR9 Monoclonal Antibody (C9Mab-11) by 2 × Alanine Scanning

Y Isoda, T Tanaka, H Suzuki, T Asano… - Monoclonal …, 2023 - liebertpub.com
We recently developed a novel anti-human CC chemokine receptor 9 (hCCR9) monoclonal
antibody (mAb), C9Mab-11, which is applicable to flow cytometry, western blotting, and …

Epitope Mapping Using the Cell-Based 2 × Alanine Substitution Method About the Anti-mouse CXCR6 Monoclonal Antibody, Cx6Mab-1

Y Isoda, T Tanaka, H Suzuki, T Asano… - Monoclonal …, 2023 - liebertpub.com
An anti-mouse CXC chemokine receptor 6 (mCXCR6) monoclonal antibody (mAb), Cx6Mab-
1, was developed recently. Cx6Mab-1 is applicable for flow cytometry, Western blotting, and …

Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies Using Flow Cytometry

N Tateyama, T Asano, H Suzuki, G Li, T Yoshikawa… - Antibodies, 2022 - mdpi.com
The CC chemokine receptor 3 (CCR3) is a receptor for CC chemokines, including
CCL5/RANTES, CCL7/MCP-3, and CCL11/eotaxin. CCR3 is expressed on the surface of …

Identification of the Binding Epitope of an Anti-Mouse CCR6 Monoclonal Antibody (C6Mab-13) Using 1× Alanine Scanning

T Tanaka, M Tawara, H Suzuki, MK Kaneko, Y Kato - Antibodies, 2023 - mdpi.com
CC chemokine receptor 6 (CCR6) is one of the members of the G-protein-coupled receptor
(GPCR) family that is upregulated in many immune-related cells, such as B lymphocytes …

Epitope Mapping of the Anti-Human CCR2 Monoclonal Antibody C2Mab-9

T Tanaka, G Li, T Asano, MK Kaneko… - Monoclonal Antibodies …, 2022 - liebertpub.com
CC chemokine receptor type-2 (CCR2) belongs to the G protein-coupled receptors
superfamily, localized on cell surface of some immune-related cells, including monocytes …

Establishment of a Sensitive Monoclonal Antibody Against Mouse CCR9 (C9Mab-24) for Flow Cytometry

H Kobayashi, T Asano, H Suzuki, T Tanaka… - Monoclonal …, 2023 - liebertpub.com
The CC chemokine receptor 9 (CCR9), also known as CD199, is one of chemokine
receptors. The CC chemokine ligand 25 (CCL25) is known to be the only ligand for CCR9 …

Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C9Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method

H Kobayashi, T Asano, T Tanaka, H Suzuki… - Antibodies, 2023 - mdpi.com
CC chemokine receptor 9 (CCR9) is a receptor for CC-chemokine ligand 25 (CCL25). CCR9
is crucial in the chemotaxis of immune cells and inflammatory responses. Moreover, CCR9 …