Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

Doxorubicin is a chemotherapeutic drug used for the treatment of various malignancies;
however, patients can experience cardiotoxic effects and this has limited the use of this …

Pyroptosis, a type of Gasdermin-mediated cell death, contributes to an exacerbation of
inflammation. To test the hypothesis that GSDME-mediated pyroptosis aggravates the …

The concept of cell death has been expanded beyond apoptosis and necrosis to additional
forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death …

Background Pyroptosis is a new programmed cell death discovered in recent years.
Pyroptosis plays an important role in various diseases. Nevertheless, there are few …

Aim Myocardial infarction (MI) is a severe disease with increased mortality and disability
rates, posing heavy economic burden for society. Exosomes were uncovered to mediate …

Kawasaki disease (KD) is the most common cause of pediatric cardiac disease in developed
countries, and can lead to permanent coronary artery damage and long term sequelae such …

Acute respiratory distress syndrome (ARDS), a devastating complication of numerous
conditions, is often associated with high mortality. It is well known that endothelial cell (EC) …

Pyroptosis is a form of programmed cell death activated by various stimuli and is
characterized by inflammasome assembly, membrane pore formation, and the secretion of …

Background The NOD–like receptor pyrin domain–containing protein 3 (NLRP3)
inflammasome activation–mediated pyroptosis pathway has been linked to myocardial …