Clinical trials of antiangiogenesis therapy in recurrent/persistent and metastatic cervical cancer

JK Alldredge, KS Tewari - The Oncologist, 2016 - academic.oup.com
Background. Treatment options for women with metastatic, persistent, or recurrent cervical
cancer are limited and thus the disease portends a poor prognosis. It is critical to understand …

miR424-5p functions as an anti-oncogene in cervical cancer cell growth by targeting KDM5B via the Notch signaling pathway

Y Zhou, Q An, R Guo, Y Qiao, L Li, X Zhang, X Zhao - Life sciences, 2017 - Elsevier
Aims Aberrant expression of miRNAs exert the critical roles in carcinogenesis, including
cervical cancer. Recent study corroborated the down-regulation of miR424-5p in uterine …

Downregulation of hsa_circ_0007534 restricts the proliferation and invasion of cervical cancer through regulating miR-498/BMI-1 signaling

X Rong, W Gao, X Yang, J Guo - Life sciences, 2019 - Elsevier
Aims Hsa_circ_0007534 has been reported to be a novel cancer-related circRNA affecting
multiple cancers. However, little is known about the role of hsa_circ_0007534 in cervical …

[HTML][HTML] A novel miRNA identified in GRSF1 complex drives the metastasis via the PIK3R3/AKT/NF-κB and TIMP3/MMP9 pathways in cervical cancer cells

Q Sun, Z Yang, P Li, X Wang, L Sun, S Wang… - Cell death & …, 2019 - nature.com
Abstract microRNAs (miRNAs) play an important role in carcinogenesis. Typically, miRNAs
downregulate the target expression by binding to the 3′ UTR of mRNAs. However, recent …

miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7

X Liu, L Gan, J Zhang - Chemico-Biological Interactions, 2019 - Elsevier
Dysregulation of miR-543 has been implicated to play crucial roles in various human
cancers. However, the function of miR-543 involved in cervical cancer (CC) progress …

Understanding the role of miRNAs in cervical cancer pathogenesis and therapeutic responses

P Chauhan, S Pramodh, A Hussain, D Elsori… - Frontiers in Cell and …, 2024 - frontiersin.org
Cervical cancer (CC) is the most common cancer in women and poses a serious threat to
health. Despite familiarity with the factors affecting its etiology, initiation, progression …

[HTML][HTML] MicroRNA‑432 is downregulated in cervical cancer and directly targets FN1 to inhibit cell proliferation and invasion

S Wang, B Gao, H Yang, X Liu, X Wu… - Oncology …, 2019 - spandidos-publications.com
Numerous studies have identified the dysregulation of microRNAs (miRNAs) in cervical
cancer, and dysregulated miRNAs are involved in regulating a number of tumour‑​ …

[HTML][HTML] Epigallocatechin gallate inhibits cell growth and regulates miRNA expression in cervical carcinoma cell lines infected with different high‑risk human …

Y Zhu, Y Huang, M Liu, Q Yan… - Experimental and …, 2019 - spandidos-publications.com
The aim of the present study was to investigate the inhibitory effects of the polyphenol
epigallocatechin‑3‑gallate (EGCG) on the growth of cervical carcinoma cell lines infected …

miR-139-5p functions as a tumor suppressor in cervical cancer by targeting TCF4 and inhibiting Wnt/β-catenin signaling

X Ji, H Guo, S Yin, H Du - OncoTargets and therapy, 2019 - Taylor & Francis
Objectives Dysregulation of microRNAs (miRNAs) has been recognized as a crucial
biological event in the development of cervical cancer (CC). miR-139-5p was identified as a …

[HTML][HTML] MiR-125 inhibited cervical cancer progression by regulating VEGF and PI3K/AKT signaling pathway

K Fu, L Zhang, R Liu, Q Shi, X Li, M Wang - World journal of surgical …, 2020 - Springer
Background MiR-125 has been shown to be involved in a variety of cancers, including
cervical cancer (CC). Here, our goal was to explore miR-125 functional role and molecular …