Risk stratification and early detection biomarkers for precision HCC screening

YT Lee, N Fujiwara, JD Yang, Y Hoshida - Hepatology, 2023 - journals.lww.com
Hepatocellular carcinoma (HCC) mortality remains high primarily due to late diagnosis as a
consequence of failed early detection. Professional societies recommend semi‐annual HCC …

[HTML][HTML] Utility of combining PIVKA-II and AFP in the surveillance and monitoring of hepatocellular carcinoma in the Asia-Pacific region

BN Toan, CK Tan, I Hasan, L Setiawan… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Even though the combined use of ultrasound (US) and alpha-fetoprotein (AFP) is
recommended for the surveillance of hepatocellular carcinoma (HCC), the utilization of AFP …

[PDF][PDF] 中国人群肝癌筛查指南(2022, 北京)

赫捷, 陈万青, 沈洪兵, 李霓, 曲春枫, 石菊芳, 孙凤… - 中华肿瘤杂志, 2022 - dzrmyy.com
中国人群的肝癌存在生存率低, 死亡率高的情况, 如何有效降低肝癌相关负担仍是中国公共卫生
和慢性病防控领域亟待解决的重大问题, 而肝癌人群筛查策略优化是值得持续探索的重要抓手和 …

[PDF][PDF] Multimarker Panels for Detection of Early Stage Hepatocellular Carcinoma: A Prospective, Multicenter, Case‐Control Study

T Piratvisuth, T Tanwandee… - Hepatology …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC), the sixth most common cancer worldwide, has an
incidence rate equal to mortality. Over 80% of HCC cases occur within a high‐risk …

Prothrombin induced by vitamin K Absence-II versus alpha-fetoprotein in detection of both resectable hepatocellular carcinoma and early recurrence after curative …

MD Wang, LY Sun, GJ Qian, C Li, LH Gu… - International Journal of …, 2022 - Elsevier
Background Alpha-fetoprotein (AFP) and prothrombin induced by vitamin K absence-II
(PIVKA-II) are two commonly used biomarkers for detection and prognostic prediction of …

The combination of PIVKA‐II and AFP improves the detection accuracy for HCC in HBV caucasian cirrhotics on long‐term oral therapy

A Loglio, M Iavarone, F Facchetti, D Di Paolo… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Protein induced by vitamin K absence or antagonist‐II (PIVKA‐
II) has been suggested as a serum biomarker for hepatocellular carcinoma (HCC) in Asian …

Serum tumor markers for early diagnosis of primary hepatocellular carcinoma

J Zong, Z Fan, Y Zhang - Journal of hepatocellular carcinoma, 2020 - Taylor & Francis
Primary hepatocellular carcinoma (HCC) is one of the most frequently occurring pernicious
tumors in the world. It is typically very insidious in the early stages with no obvious …

[HTML][HTML] Usefulness of PIVKA-II for monitoring after liver transplantation in patients with hepatocellular carcinoma

F Villalba-López, LF Sáenz-Mateos… - Scientific Reports, 2023 - nature.com
The high morbidity and mortality of hepatocellular carcinoma (HCC) has encouraged the
search for new biomarkers to be used alongside alpha-foetoprotein (AFP) and imaging tests …

Gut microbial signatures of patients with primary hepatocellular carcinoma and their healthy first-degree relatives

J Feng, Y Wu, P Dai, D Wang, L Liu… - Journal of Applied …, 2023 - academic.oup.com
Aims The gut microbiome has been recognized as a significant contributor to primary
hepatocellular carcinoma (HCC), with mounting evidence indicating associations between …

[HTML][HTML] Diagnostic value of fibrinogen to prealbumin ratio and gamma-glutamyl transpeptidase to platelet ratio in the progression of AFP-negative hepatocellular …

L Huang, Z Mo, Z Hu, L Zhang, S Qin, X Qin… - Cancer Cell …, 2020 - Springer
Background This study aimed to comprehensively assess the diagnostic value of fibrinogen
to prealbumin ratio (FPR) and gamma-glutamyl transpeptidase to platelet ratio (GPR) as …