West syndrome: a comprehensive review
P Pavone, A Polizzi, SD Marino, G Corsello… - Neurological …, 2020 - Springer
Since its first clinical description (on his son) by William James West (1793–1848) in 1841,
and the definition of the classical triad of (1) infantile spasms;(2) hypsarrhythmia, and (3) …
and the definition of the classical triad of (1) infantile spasms;(2) hypsarrhythmia, and (3) …
Infantile spasms: outcome in clinical studies
R Riikonen - Pediatric neurology, 2020 - Elsevier
Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …
infantile spasms include primary response to treatment, relapse of spasms, neurological …
[HTML][HTML] Treatment of infantile spasm syndrome: update from the interdisciplinary guideline committee coordinated by the German-speaking Society of Neuropediatrics
G Ramantani, BK Bölsterli, M Alber, J Klepper… - …, 2022 - thieme-connect.com
Objectives The manuscript serves as an update on the current management practices for
infantile spasm syndrome (ISS). It includes a detailed summary of the level of current …
infantile spasm syndrome (ISS). It includes a detailed summary of the level of current …
Effectiveness of corticosteroids versus adrenocorticotropic hormone for infantile spasms: a systematic review and meta‐analysis
YH Chang, C Chen, SH Chen… - Annals of Clinical and …, 2019 - Wiley Online Library
Objective To compare the therapeutic effectiveness of oral corticosteroids with that of
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …
Prednisolone/prednisone as adrenocorticotropic hormone alternative for infantile spasms: a meta‐analysis of randomized controlled trials
S Li, X Zhong, S Hong, T Li… - Developmental Medicine & …, 2020 - Wiley Online Library
Aim To compare the efficacy and safety of prednisolone/prednisone and adrenocorticotropic
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …
Treating infantile spasms with high-dose oral corticosteroids: a retrospective review of 87 children
E Gonzalez-Giraldo, CE Stafstrom, AC Stanfield… - Pediatric …, 2018 - Elsevier
Background Hormonal therapy is the treatment of choice in most patients with infantile
spasms, but the optimal way to provide this therapy is unclear. Intramuscular …
spasms, but the optimal way to provide this therapy is unclear. Intramuscular …
Epilepsy outcome at four years in a randomized clinical trial comparing oral prednisolone and intramuscular ACTH in west syndrome
Background This article explores the role of initial treatment on control of spasms and other
epilepsies at four years in children previously treated for West syndrome. Methods The Sri …
epilepsies at four years in children previously treated for West syndrome. Methods The Sri …
Modeling epileptic spasms during infancy: Are we heading for the treatment yet?
L Velíšek, J Velíšková - Pharmacology & therapeutics, 2020 - Elsevier
Infantile spasms (IS or epileptic spasms during infancy) were first described by Dr. William
James West (aka West syndrome) in his own son in 1841. While rare by definition (occurring …
James West (aka West syndrome) in his own son in 1841. While rare by definition (occurring …
Treatment of infantile spasms: why do we know so little?
N Specchio, N Pietrafusa, A Ferretti… - Expert review of …, 2020 - Taylor & Francis
Introduction Infantile spasm (IS) is an epileptic syndrome with typical onset within the first 2
years of life. This condition might be caused by several etiologies. IS is associated with …
years of life. This condition might be caused by several etiologies. IS is associated with …
Very-high-dose prednisolone before ACTH for treatment of infantile spasms: evaluation of a standardized protocol
Y Eliyan, J Heesch, A Alayari, RR Rajaraman… - Pediatric …, 2019 - Elsevier
Background There is ongoing debate regarding the comparative effectiveness of
adrenocorticotropic hormone and prednisolone in the treatment of infantile spasms. With a …
adrenocorticotropic hormone and prednisolone in the treatment of infantile spasms. With a …