Angiogenic effects and crosstalk of adipose-derived mesenchymal stem/stromal cells and their extracellular vesicles with endothelial cells

S Rautiainen, T Laaksonen, R Koivuniemi - International Journal of …, 2021 - mdpi.com
Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …

[HTML][HTML] Potential angiogenic, immunomodulatory, and antifibrotic effects of mesenchymal stem cell-derived extracellular vesicles in systemic sclerosis

K Zhao, C Kong, N Shi, J Jiang, P Li - Frontiers in Immunology, 2023 - frontiersin.org
Systemic sclerosis (SSc) is an intricate systemic autoimmune disease with pathological
features such as vascular injury, immune dysregulation, and extensive fibrosis of the skin …

Exosomal miR-532–5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5

G Zhu, X Yang, C Peng, L Yu, Y Hao - Experimental cell research, 2020 - Elsevier
The transplantation of bone marrow mesenchymal stem cells (BMSCs) has been found to be
used as an effective therapy of intervertebral disc degeneration (IDD). However, the …

[HTML][HTML] Long non-coding RNA MALAT1 regulates cardiomyocytes apoptosis after hypoxia/reperfusion injury via modulating miR-200a-3p/PDCD4 axis

R Sun, L Zhang - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) have been reported to be crucial modulators in various
heart diseases, including myocardial infarction (MI). LncRNA metastasis associated lung …

Cell type–specific microRNA therapies for myocardial infarction

B Liu, B Wang, X Zhang, R Lock, T Nash… - Science translational …, 2021 - science.org
Current interventions fail to recover injured myocardium after infarction and prompt the need
for development of cardioprotective strategies. Of increasing interest is the therapeutic use of …

[HTML][HTML] microRNAs associated to anthracycline-induced cardiotoxicity in women with breast cancer: A systematic review and pathway analysis

JD Pereira, JAG Tosatti, R Simoes, MR Luizon… - Biomedicine & …, 2020 - Elsevier
Background Cardiotoxicity is a common and serious adverse effect of anthracycline therapy
in breast cancer patients. The current criteria for cardiotoxicity are based on imaging and …

Long non‑coding RNA GAS5 regulates myocardial ischemia‑reperfusion injury through the PI3K/AKT apoptosis pathway by sponging miR‑532‑5p

Y Han, N Wu, F Xia, S Liu, D Jia - … Journal of Molecular …, 2020 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) have been revealed to have a marked effect in
cardiovascular diseases, including during cardiac development, cardiac hypertrophy …

MicroRNA miR-212 regulates PDCD4 to attenuate Aβ25–35-induced neurotoxicity via PI3K/AKT signaling pathway in Alzheimer's disease

Y Wang, Q Chang - Biotechnology Letters, 2020 - Springer
Background Alzheimer's disease (AD) is a progressive neurodegenerative disease in the
elderly. MicroRNA (miRNA) miR-212-3p (miR-212) has been reported to dysregulated in …

MicroRNA and their target mRNAs change expression in whole blood of patients after intracerebral hemorrhage

X Cheng, BP Ander, GC Jickling… - Journal of Cerebral …, 2020 - journals.sagepub.com
Previous studies showed changes in mRNA levels in whole blood of rats and humans, and
in miRNA in whole blood of rats following intracerebral hemorrhage (ICH). Thus, this study …

CircCHMP5 contributes to Ox-LDL-induced endothelial cell injury through the regulation of MiR-532-5p/ROCK2 axis

X Li, X Kang, Y Di, S Sun, L Yang, B Wang… - Cardiovascular drugs and …, 2023 - Springer
Background Aberrant expression of circular RNA (circRNA) has been demonstrated to be
related to atherosclerosis (AS) formation. However, the mechanism of circCHMP5 (also …