[HTML][HTML] The potential of surface-immobilized antimicrobial peptides for the enhancement of orthopaedic medical devices: a review

B Skerlavaj, G Boix-Lemonche - Antibiotics, 2023 - mdpi.com
Due to the well-known phenomenon of antibiotic resistance, there is a constant need for
antibiotics with novel mechanisms and different targets respect to those currently in use. In …

A homogeneous dopamine–silver nanocomposite coating: striking a balance between the antibacterial ability and cytocompatibility of dental implants

S Wang, Z Wu, Y Wang, H Hong, L Zhang… - Regenerative …, 2023 - academic.oup.com
Silver has been widely used for surface modification to prevent implant-associated
infections. However, the inherent cytotoxicity of silver greatly limited the scope of its clinical …

[HTML][HTML] Polymer Conjugates of Antimicrobial Peptides (AMPs) with d-Amino Acids (d-aa): State of the Art and Future Opportunities

O Bellotto, S Semeraro, A Bandiera, F Tramer, N Pavan… - Pharmaceutics, 2022 - mdpi.com
In recent years, antimicrobial peptides (AMPs) have enjoyed a renaissance, as the world is
currently facing an emergency in terms of severe infections that evade antibiotics' treatment …

[HTML][HTML] Effect of Camel Peptide on the Biofilm of Staphylococcus epidermidis and Staphylococcus haemolyticus Formed on Orthopedic Implants

J Nowicka, A Janczura, M Pajączkowska, G Chodaczek… - Antibiotics, 2023 - mdpi.com
The increasing bacterial drug resistance and the associated challenges in the treatment of
infections warrant the search for alternative therapeutic methods. Hope is placed in …

How can biomaterial-conjugated antimicrobial peptides fight bacteria and be protected from degradation?

PM Alves, CC Barrias, P Gomes, MCL Martins - Acta Biomaterialia, 2024 - Elsevier
The emergence of antibiotic-resistant bacteria is a serious threat to public health.
Antimicrobial peptides (AMP) are a powerful alternative to antibiotics due to their low …

Growth factor-functionalized titanium implants for enhanced bone regeneration: A review

Z Che, Q Sun, Z Zhao, Y Wu, H Xing, K Song… - International Journal of …, 2024 - Elsevier
Titanium and titanium alloys are widely favored materials for orthopedic implants due to their
exceptional mechanical properties and biological inertness. The additional benefit of …

[HTML][HTML] Influence of Immobilization Strategies on the Antibacterial Properties of Antimicrobial Peptide-Chitosan Coatings

M Barbosa, PM Alves, F Costa, C Monteiro, P Parreira… - Pharmaceutics, 2023 - mdpi.com
It is key to fight bacterial adhesion to prevent biofilm establishment on biomaterials. Surface
immobilization of antimicrobial peptides (AMP) is a promising strategy to avoid bacterial …

[HTML][HTML] Surgical applications of materials engineered with antimicrobial properties

DP Perrault, A Sharma, JF Kim, GC Gurtner, DC Wan - Bioengineering, 2022 - mdpi.com
The infection of surgically placed implants is a problem that is both large in magnitude and
that broadly affects nearly all surgical specialties. Implant-associated infections deleteriously …

[HTML][HTML] Antimicrobial Peptides and Their Assemblies

AM Carmona-Ribeiro - Future Pharmacology, 2023 - mdpi.com
Antibiotic resistance requires alternatives to fight multi-drug resistant strains. Antimicrobial
peptides (AMPs) act by disrupting or solubilizing microbial cell walls or membranes in …

On‐Demand Magnetically‐Activated Drug Delivery from Additively Manufactured Porous Bone Implants to Tackle Antibiotic‐Resistant Infections

M Šalandová, MA Leeflang… - Advanced Materials …, 2024 - Wiley Online Library
This study proposes a new concept for an on‐demand drug releasing device intended for
integration into additively manufactured (ie, 3D printed) orthopedic implants. The system …