Amorphous solid dispersions: Stability mechanism, design strategy and key production technique of hot melt extrusion

J Han, M Tang, Y Yang, W Sun, Z Yue, Y Zhang… - International Journal of …, 2023 - Elsevier
Solid dispersion (SD) system has been used as an effective formulation strategy to increase
in vitro and in vivo performances of poorly water-soluble drugs, such as …

An isocratic RP-HPLC-UV method for simultaneous quantification of tizanidine and lidocaine: application to in vitro release studies of a subcutaneous implant

CJ Picco, QK Anjani, RF Donnelly, E Larrañeta - Analytical Methods, 2024 - pubs.rsc.org
Implantable devices have been widely investigated to improve the treatment of multiple
diseases. Even with low drug loadings, these devices can achieve effective delivery and …

Evaluation of Printability of PVA-Based Tablets from Powder and Assessment of Critical Rheological Parameters

J Lenhart, F Pöstges, KG Wagner, DJ Lunter - Pharmaceutics, 2024 - mdpi.com
Fused deposition modeling (FDM) is a rather new technology in the production of
personalized dosage forms. The melting and printing of polymer–active pharmaceutical …

Polymer-mediated solubility enhancement and supersaturation stabilization using various hydroxypropyl cellulose grades within amorphous solid dispersions

F Pöstges - 2024 - bonndoc.ulb.uni-bonn.de
Solubility enhancement in combination with supersaturation stabilization of poorly soluble
drugs is a well-established concept to enhance oral bioavailability. One promising …

Free-D Molding: Every Idea Deserves a Prototype

A Bramböck, D Treffer - … and Functionality of Polymeric Excipients in Drug …, 2023 - Springer
Abstract 3D printing is changing the world. However, the progress for pharmaceutical
applications is slower than in other industries. It comes with unique challenges previously …

[PDF][PDF] Analytical Methods

QK Anjani, E Larrañeta - 2024 - pure.qub.ac.uk
Implantable devices have been widely investigated to improve the treatment of multiple
diseases. Even with low drug loadings, these devices can achieve effective delivery and …