Amelioration of cancer employing chitosan, its derivatives, and chitosan-based nanoparticles: recent updates

T Virmani, G Kumar, A Sharma, K Pathak, MS Akhtar… - Polymers, 2023 - mdpi.com
The limitations associated with the conventional treatment of cancer have necessitated the
design and development of novel drug delivery systems based mainly on nanotechnology …

Translational aspect in peptide drug discovery and development: An emerging therapeutic candidate

U Anand, A Bandyopadhyay, NK Jha… - Biofactors, 2023 - Wiley Online Library
In the last two decades, protein–protein interactions (PPIs) have been used as the main
target for drug development. However, with larger or superficial binding sites, it has been …

[HTML][HTML] Cellular landscaping of cisplatin resistance in cervical cancer

R Bhattacharjee, T Dey, L Kumar, S Kar… - Biomedicine & …, 2022 - Elsevier
Cervical cancer (CC) caused by human papillomavirus (HPV) is one of the largest causes of
malignancies in women worldwide. Cisplatin is one of the widely used drugs for the …

[HTML][HTML] Current research status of anti-cancer peptides: Mechanism of action, production, and clinical applications

RK Chinnadurai, N Khan, GK Meghwanshi… - Biomedicine & …, 2023 - Elsevier
The escalating rate of cancer cases, together with treatment deficiencies and long-term side
effects of currently used cancer drugs, has made this disease a global burden of the 21st …

Bridging the gap between tumor-on-chip and clinics: a systematic review of 15 years of studies

C Bouquerel, A Dubrova, I Hofer, DTT Phan… - Lab on a Chip, 2023 - pubs.rsc.org
Over the past 15 years, the field of oncology research has witnessed significant progress in
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …

Biomedical, clinical and environmental applications of platinum-based nanohybrids: An updated review

ST Yerpude, AK Potbhare, P Bhilkar, AR Rai… - Environmental …, 2023 - Elsevier
Abstract Platinum nanoparticles (Pt NPs) have numerous applications in various sectors,
including pharmacology, nanomedicine, cancer therapy, radiotherapy, biotechnology and …

Plant-derived exosomes: a green approach for cancer drug delivery

S Madhan, R Dhar, A Devi - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Plant-derived exosomes (PDEs) are natural extracellular vesicles (EVs). In the current
decade, they have been highlighted for cancer therapeutic development. Cancer is a global …

Anticancer and antibacterial activities of embelin: Micro and nano aspects

M Alavi, F Martinez, DR Delgado… - Micro Nano Bio …, 2022 - mnba-journal.com
There are some reported anticancer and antibacterial effects for embelin, although, it's poor
aqueous solubility and bioavailability are main hindrance to apply embelin in therapeutics …

Codelivery of phytochemicals with conventional anticancer drugs in form of nanocarriers

G Kumar, T Virmani, A Sharma, K Pathak - Pharmaceutics, 2023 - mdpi.com
Anticancer drugs in monotherapy are ineffective to treat various kinds of cancer due to the
heterogeneous nature of cancer. Moreover, available anticancer drugs possessed various …

Drug delivery systems for localized cancer combination therapy

RN Woodring, EG Gurysh, EM Bachelder… - ACS applied bio …, 2023 - ACS Publications
With over 2 million cancer cases and over 600,000 cancer-associated deaths predicted in
the US for 2022, this life-debilitating disease continuously impacts the lives of people across …