An overview of artificial intelligence techniques for diagnosis of Schizophrenia based on magnetic resonance imaging modalities: Methods, challenges, and future …
Schizophrenia (SZ) is a mental disorder that typically emerges in late adolescence or early
adulthood. It reduces the life expectancy of patients by 15 years. Abnormal behavior …
adulthood. It reduces the life expectancy of patients by 15 years. Abnormal behavior …
Assessment of noninvasive brain stimulation interventions for negative symptoms of schizophrenia: a systematic review and network meta-analysis
Importance Negative symptoms have a detrimental impact on functional outcomes and
quality of life in people with schizophrenia, and few therapeutic options are considered …
quality of life in people with schizophrenia, and few therapeutic options are considered …
Pathophysiology of negative symptom dimensions of schizophrenia–current developments and implications for treatment
Negative symptoms of schizophrenia comprise a group of severe symptoms contributing to
high disease burden and poor long-term prognosis. Conceptual work has shown that these …
high disease burden and poor long-term prognosis. Conceptual work has shown that these …
Updated perspectives on the clinical significance of negative symptoms in patients with schizophrenia
GM Giordano, E Caporusso, P Pezzella… - Expert Review of …, 2022 - Taylor & Francis
Introduction Negative symptoms in schizophrenia are associated with poor response to
available treatments, poor quality of life, and functional outcome. Therefore, they represent a …
available treatments, poor quality of life, and functional outcome. Therefore, they represent a …
Atypical antipsychotics antagonize GABAA receptors in the ventral tegmental area GABA neurons to relieve psychotic behaviors
C Lu, X Zhu, Y Feng, W Ao, J Li, Z Gao, H Luo… - Molecular …, 2023 - nature.com
Psychosis is an abnormal mental condition that can cause patients to lose contact with
reality. It is a common symptom of schizophrenia, bipolar disorder, sleep deprivation, and …
reality. It is a common symptom of schizophrenia, bipolar disorder, sleep deprivation, and …
[HTML][HTML] Circuit-based approaches to understanding corticostriatothalamic dysfunction across the psychosis continuum
Dopamine is known to play a role in the pathogenesis of psychotic symptoms, but the
mechanisms driving dopaminergic dysfunction in psychosis remain unclear. Considerable …
mechanisms driving dopaminergic dysfunction in psychosis remain unclear. Considerable …
Abnormal development and dysconnectivity of distinct thalamic nuclei in patients with 22q11. 2 deletion syndrome experiencing auditory hallucinations
Background Several studies in patients with schizophrenia have demonstrated an abnormal
thalamic volume and thalamocortical connectivity. Specifically, hyperconnectivity with …
thalamic volume and thalamocortical connectivity. Specifically, hyperconnectivity with …
Electrophysiological correlates of reward anticipation in subjects with schizophrenia: an erp microstate study
A Perrottelli, GM Giordano, T Koenig, E Caporusso… - Brain topography, 2024 - Springer
The current study aimed to investigate alterations of event-related potentials (ERPs)
microstate during reward anticipation in subjects with schizophrenia (SCZ), and their …
microstate during reward anticipation in subjects with schizophrenia (SCZ), and their …
Factors influencing the outcome of integrated therapy approach in schizophrenia: A narrative review of the literature
GM Giordano, F Brando, P Pezzella… - Frontiers in …, 2022 - frontiersin.org
The integration of pharmacotherapy with psychosocial interventions has an important role to
play in the improvement of functional outcome of subjects with schizophrenia (SCZ), in all …
play in the improvement of functional outcome of subjects with schizophrenia (SCZ), in all …
Negative symptoms of schizophrenia and dopaminergic transmission: translational models and perspectives opened by iPSC techniques
Negative symptoms (NS) represent a heterogeneous dimension of schizophrenia (SCZ),
associated with a poor functional outcome. A dysregulated dopamine (DA) system, including …
associated with a poor functional outcome. A dysregulated dopamine (DA) system, including …