The potential of endurance exercise-derived exosomes to treat metabolic diseases
A Safdar, A Saleem, MA Tarnopolsky - Nature Reviews Endocrinology, 2016 - nature.com
Endurance exercise-mediated multisystemic adaptations are known to mitigate metabolism-
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …
Molecular mechanisms of cardiac remodeling and regeneration in physical exercise
D Schüttler, S Clauss, LT Weckbach, S Brunner - Cells, 2019 - mdpi.com
Regular physical activity with aerobic and muscle-strengthening training protects against the
occurrence and progression of cardiovascular disease and can improve cardiac function in …
occurrence and progression of cardiovascular disease and can improve cardiac function in …
Physical exercise and epigenetic modifications in skeletal muscle
Physical activity and sports play major roles in the overall health status of humans. It is well
known that regular exercise helps to lower the risk for a broad variety of health problems …
known that regular exercise helps to lower the risk for a broad variety of health problems …
Exosomes as mediators of the systemic adaptations to endurance exercise
A Safdar, MA Tarnopolsky - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Habitual endurance exercise training is associated with multisystemic metabolic adaptations
that lower the risk of inactivity-associated disorders such as obesity and type 2 diabetes …
that lower the risk of inactivity-associated disorders such as obesity and type 2 diabetes …
[HTML][HTML] Biogenesis and function of extracellular vesicles in pathophysiological processes of skeletal muscle atrophy
W Wang, M Li, Z Chen, L Xu, M Chang, K Wang… - Biochemical …, 2022 - Elsevier
Pathophysiological changes of skeletal muscle occur in a variety of chronic diseases,
leading to muscle atrophy and dysfunction, which greatly affect the quality of life. Despite …
leading to muscle atrophy and dysfunction, which greatly affect the quality of life. Despite …
Noncoding RNAs in cardiovascular disease: current knowledge, tools and technologies for investigation, and future directions: a scientific statement from the american …
Background: The discovery that much of the non–protein-coding genome is transcribed and
plays a diverse functional role in fundamental cellular processes has led to an explosion in …
plays a diverse functional role in fundamental cellular processes has led to an explosion in …
Understanding key mechanisms of exercise-induced cardiac protection to mitigate disease: current knowledge and emerging concepts
BC Bernardo, JYY Ooi, KL Weeks… - Physiological …, 2018 - journals.physiology.org
The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …
demonstrated that exercise is an intervention that can improve cardiac function in heart …
Normalization strategies differently affect circulating miRNA profile associated with the training status
M Faraldi, M Gomarasca, V Sansoni, S Perego… - Scientific Reports, 2019 - nature.com
MicroRNAs are fine regulators of the whole-body adaptive response but their use as
biomarkers is limited by the lack of standardized pre-and post-analytical procedures. This …
biomarkers is limited by the lack of standardized pre-and post-analytical procedures. This …
[HTML][HTML] MicroRNAs as important regulators of exercise adaptation
A significant body of evidence supports the protective role of exercise training (ET) in
cardiovascular diseases, skeletal muscle dystrophies, several types of cancer, Alzheimer …
cardiovascular diseases, skeletal muscle dystrophies, several types of cancer, Alzheimer …
Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs
T Fernandes, VG Baraúna… - American Journal …, 2015 - journals.physiology.org
Left ventricular (LV) hypertrophy is an important physiological compensatory mechanism in
response to chronic increase in hemodynamic overload. There are two different forms of LV …
response to chronic increase in hemodynamic overload. There are two different forms of LV …