Shikonin is the major bioactive component extracted from the roots of Lithospermum
erythrorhizon which is also known as “Zicao” in Traditional Chinese Medicine (TCM). Recent …

Background Shikonin is one of the major phytochemical components of Lithospermum
erythrorhizon (Purple Cromwell), which is a type of medicinal herb broadly utilized in …

Currently, skin injuries have a serious impact on people's lives and socio-economic stress.
Shikonin, a naphthoquinone compound derived from the root of the traditional Chinese …

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract that consists of Crohn's disease (CD) and ulcerative colitis (UC). Cytokines are thought …

Background In diabetes mellitus, diabetic nephropathy (DN) is a typical complication and
pivotal cause of chronic kidney disease. The DN disease burden is among the highest in the …

Shikonin is the major active component in Lithospermum erythrorhizon and has
pharmacological effects including reducing inflammation, aiding resistance to bacteria and …

Modulation of inhibitor kappa B kinase-beta (IKK-β) kinase activity could be useful for
preventing inflammation that serves an efficient role in protection against cardiovascular …

One new furylhydroquinone derivative (1) and seven known compounds (2–8) were isolated
from the roots of Lithospermum erythrorhizon Sieb. et Zucc (Boraginaceae). The structure of …

Воробейник-Lithospermum officinalis L. распространенное, известное лекарственное
растение. Растение применялось в лечебных целях с глубокой древности. В древней …

Background: Sepsis causes several immunological and metabolic alterations that induce
oxidative stress. The modulation of fatty acid-binding protein 4 (FABP4) has been shown to …