Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Biodegradable materials, including natural and synthetic polymers and hydrolyzable metals,
constitute the main components of temporary, implantable medical devices. Besides the …

Over the last decade, 3D bioprinting has received immense attention from research
communities for developing functional tissues. Thanks to the complexity of tissues, various …

Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which
is of great significance to tissue development. ECM in muscle fiber niche consists of three …

During wound healing and surgical implantation, the body establishes a delicate balance
between immune activation to fight off infection and clear debris and immune tolerance to …

The host immune response to bone biomaterials is vital in determining scaffold fates and
bone regeneration outcomes. The nanometer-scale interface of biomaterials, which …

The vast opportunities for biomaterials design and functionality enabled by mimicking nature
continue to stretch the limits of imagination. As both biological understanding and …

Volumetric muscle loss (VML) is an irrecoverable injury associated with muscle loss greater
than 20%. Although hydrogel-based 3D engineered muscles and the decellularized …

Immune-mediated tissue regeneration driven by a biomaterial scaffold is emerging as an
innovative regenerative strategy to repair damaged tissues. We investigated how …

Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …